BMPR-IA/ALK-3 Antibody

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB100-41375	Applications	Species
Keller S, Nickel J, Zhang JL et al. Molecular recognition of BMP-2 and BMP receptor IA. Nat Struct Mol Biol 2004-05-01 [PMID: 15064755]

Array NB100-41375

• BMPR-IA/ALK-3 Antibodies
• BMPR-IA/ALK-3 ELISA Kits
• BMPR-IA/ALK-3 Proteins and Enzymes