BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free Summary
Immunogen |
Human recombinant BMPR-IA/ALK-3 (extracellular domain) |
Specificity |
In Western blots, this antibody shows good cross-reactivity with mouse BMPR-IA/ALK-3, but no cross-reactivity with recombinant human BMPR-IB or rhBMPR-II. |
Isotype |
IgG2 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
BMPR1A |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:50-1:200
- Western Blot 1:100-1:1000
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS |
Preservative |
No Preservative |
Concentration |
LYOPH |
Purity |
Protein G purified |
Reconstitution Instructions |
Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml. |
Alternate Names for BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free
Background
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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Isotype Controls
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