BMI-1 Antibody (LLBmi1-1) [DyLight 488] Summary
Immunogen |
Human Bmi1 protein [Swiss-Prot# P35226] |
Localization |
Nucleus. Cytoplasm. |
Isotype |
IgG2b Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
BMI1 |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Chromatin Immunoprecipitation (ChIP)
- Flow (Intracellular)
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence
- Immunoprecipitation
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein G purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for BMI-1 Antibody (LLBmi1-1) [DyLight 488]
Background
Bmi1 is a member of the polycomb group (PcG) multiprotein PRC1 complex which functions to control axial skeleton development through Hox gene repression. Bmi1 plays an important role in repressing the transcription of the p16Ink4a and p19Arf genes and is required to maintain the proliferative and self-renewal properties of adult hematopoietic and neural stem cells. Bmi1 is an oncogene whose overexpression has been associated with many types of human tumors, including those in breast, colorectal, prostate, and non-small cell lung cancers. As seen in many recent publications, Bmi1 antibodies can serve as useful research tools to study Bmi1 and its effect on tumor proliferation and tumorigenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for BMI-1 Antibody (NBP1-96140G) (0)
Secondary Antibodies
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