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beta-Defensin 3 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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beta-Defensin 3 Antibody Summary

Description
This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Immunogen
Produced in rabbits immunized with purified, recombinant Human beta-Defensin 3 (Uniprot#: P81534; Gly23-Lys6).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DEFB103B
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:5000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 um filtered solution in PBS
Preservative
No Preservative
Purity
Antigen and protein A Affinity-purified

Alternate Names for beta-Defensin 3 Antibody

  • BD14
  • BD3
  • BD-3
  • beta-defensin 103
  • betaDefensin 3
  • beta-Defensin 3
  • DEFB103
  • DEFB103A
  • DEFB103B
  • DEFB3
  • DEFB-3
  • DEFB3DEFB103A
  • Defensin, beta 103
  • defensin, beta 103B
  • Defensin-like protein
  • HBD-3
  • HBD3HBP3

Background

Defensin beta 3 is a novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and clones from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomyosin-resistant Entoerococcus faecium. Keratinocytes and airway epithelial cells are cellular sources of hBD-3. Tumor necrosis factor alpha and contact with bacteria were found to induce hBD-3 mRNA expression. hBD-3, therefore, might be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung, such as cystic fibrosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for beta-Defensin 3 Antibody (NBP3-06517) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for beta-Defensin 3 Antibody (NBP3-06517)

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Blogs on beta-Defensin 3.

Beta-defensin-3: I may be small but I'm powerful!
Beta-defensin 3 is a novel, non-hemolytic antimicrobial cationic peptide originally isolated from human lesional psoriatic scales and keratinocyte clones. It is a very small (2-6 kD) yet potent salt-insensitive broad spectrum antimicrobial that ta...  Read full blog post.

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Bioinformatics

Gene Symbol DEFB103B