Orthogonal Strategies: Immunohistochemistry-Paraffin: Bcl-6 Antibody [NBP2-59786] - Staining in human tonsil and pancreas tissues . Corresponding BCL6 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: Bcl-6 Antibody [NBP2-59786] - Human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Bcl-6 Antibody [NBP2-59786] - Staining of human lymphoma, non-Hodgkin's type, shows strong nuclear positivity in tumor cells.
Immunohistochemistry-Paraffin: Bcl-6 Antibody [NBP2-59786] - Human tonsil shows strong nuclear positivity in germinal center cells.
Immunohistochemistry-Paraffin: Bcl-6 Antibody [NBP2-59786] - Human lymph node shows strong nuclear positivity in germinal center cells.
Immunohistochemistry-Paraffin: Bcl-6 Antibody [NBP2-59786] - Human pancreas shows no positivity as expected.
Immunohistochemistry-Paraffin: Bcl-6 Antibody [NBP2-59786] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
This antibody was developed against a recombinant protein corresponding to the amino acid sequence: NIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNS
Predicted Species
Mouse (95%), Rat (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCL6
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified
Alternate Names for Bcl-6 Antibody
B-cell CLL/lymphoma 6
B-cell lymphoma 6 protein transcript
Bcl-5
BCL5B-cell lymphoma 5 protein
Bcl6
Bcl-6
BCL6A
cys-his2 zinc finger transcription factor
LAZ3
LAZ3ZBTB27B-cell lymphoma 6 protein
lymphoma-associated zinc finger gene on chromosome 3
Protein LAZ-3
ZBTB27
Zinc finger and BTB domain-containing protein 27
Zinc finger protein 51ZNF51
zinc finger transcription factor BCL6S
ZNF51
Background
Bcl6 reacts with Bcl6 gene product in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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