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Aquaporin-2 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Aquaporin-2 Antibody [NBP2-33472] - Analysis in human kidney and colon tissues. Corresponding AQP2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Aquaporin-2 Antibody [NBP2-33472] - Staining of human prostate shows no positivity in as expected.
Immunohistochemistry-Paraffin: Aquaporin-2 Antibody [NBP2-33472] - Staining of human fallopian tube shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: Aquaporin-2 Antibody [NBP2-33472] - Staining of human colon shows no cytoplasmic positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: Aquaporin-2 Antibody [NBP2-33472] - Staining of human kidney shows moderate positivity in luminal membrane in cells in tubules.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Aquaporin-2 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: VLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSL
Predicted Species
Mouse (91%), Rat (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AQP2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Aquaporin-2 Protein (NBP2-33472PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Aquaporin-2 Antibody

  • ADH water channel
  • AQP-2
  • AQP-CD
  • aquaporin 2 (collecting duct)
  • aquaporin-2
  • aquaporin-CD
  • Collecting duct water channel protein
  • MGC34501
  • Water channel protein for renal collecting duct
  • water-channel aquaporin 2
  • WCH-CD

Background

Aquaporin 2 (AQP2) is a membrane protein that is involved in plasma membrane water transport in the renal collecting duct. Specifically, AQP2 forms a water-specific channel, providing the renal collecting duct plasma membranes with a high permeability to water and thereby permitting osmosis.

Aquaporin-2 antibodies serve as membrane markers and are useful for renal function studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol AQP2
Uniprot