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APBB3 Antibody

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Immunohistochemistry-Paraffin: APBB3 Antibody [NBP3-17683] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells and neuropil.
Immunohistochemistry-Paraffin: APBB3 Antibody [NBP3-17683] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells and neuropil.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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APBB3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQP
Predicted Species
Mouse (91%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
APBB3
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for APBB3 Antibody

  • amyloid beta (A4) precursor protein-binding, family B, member 3
  • amyloid precursor interacting protein
  • Fe65L2
  • FE65L2amyloid beta A4 precursor protein-binding family B member 3
  • FE65-like protein 2
  • MGC150555
  • MGC87674
  • Protein Fe65-like 2
  • SRA

Background

APBB3 is encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol APBB3