Apolipoprotein L1 Antibody

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1- 13.1 within a 127,000-bp region . apoL has been characterized as a pancreas specific, 383-amino acid, 42 kDa protein that contains a 12-amino acid secretory signal peptide. The apoL genes have TATA-less promoters and contain putative sterol regulatory elements, suggesting that transcription of these genes may be coordinated with that of the low density lipoprotein receptor and genes in pathways involving the synthesis of triglycerides and cholesterol. apoL homologs can undergo 10 fold changes in expression during atherosclerotic changes in vascular endothelial cells, which includes the inflammatory reaction of atherosclerotic lesions.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 3 of 3.

Publications using NBP1-89033	Applications	Species
Halfter W, Moes S, Asgeirsson DO et al. Diabetes-related changes in the protein composition and the biomechanical properties of human retinal vascular basement membranes. PLoS ONE 2017-12-28 [PMID: 29284024] (ICC/IF, Human)	ICC/IF	Human
Johnstone DB, Shegokar V, Nihalani D et al. APOL1 Null Alleles from a Rural Village in India Do Not Correlate with Glomerulosclerosis. PLoS One 2012-01-01 [PMID: 23300552]
Madhavan SM, O'Toole JF, Konieczkowski M et al. APOL1 localization in normal kidney and nondiabetic kidney disease. J Am Soc Nephrol 2011-11-01 [PMID: 21997392]

Array NBP1-89033

• Apolipoprotein L1 Antibodies
• Apolipoprotein L1 ELISA Kits
• Apolipoprotein L1 Lysates
• Apolipoprotein L1 Proteins