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ALDH1L1 Antibody

Images

 
Western Blot: ALDH1L1 Antibody [NBP1-89414] - Analysis in human cell line RT-4.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human cerebral cortex shows strong cytoplasmic positivity in astrocytes.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human kidney.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human lymph node.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human liver.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human cerebral cortex.
Independent Antibodies: Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human cerebral cortex, kidney, liver and lymph node using Anti-ALDH1L1 antibody NBP1-89414 (A) shows similar ...read more
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: ALDH1L1 Antibody [NBP1-89414] - Staining of human lymph node shows no positivity in germinal center cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

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ALDH1L1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: ILFGNDDKMLLVKNIQLEDGKMILASNFFKGAASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDF
Marker
Astrocyte Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ALDH1L1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Theoretical MW
99 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
ALDH1L1 Protein (NBP1-89414PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ALDH1L1 Antibody

  • 10-formyltetrahydrofolate dehydrogenase
  • aldehyde dehydrogenase 1 family, member L1
  • aldehyde dehydrogenase family 1 member L1
  • Cytosolic 10-formyltetrahydrofolate dehydrogenase
  • DKFZp781N0997
  • EC 1.5.1.6,10-FTHFDH
  • FDH
  • formyltetrahydrofolate dehydrogenase
  • FTHFD10-fTHF

Background

ALDH1L1 is encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ALDH1L1
Entrez
Uniprot