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alcohol dehydrogenase 5 Antibody (OTI5G4) [DyLight 594]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
OTI5G4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70096AF350
Alexa Fluor 405
NBP2-70096AF405
Alexa Fluor 488
NBP2-70096AF488
Alexa Fluor 532
NBP2-70096AF532
Alexa Fluor 594
NBP2-70096AF594
Alexa Fluor 647
NBP2-70096AF647
Alexa Fluor 700
NBP2-70096AF700
Alexa Fluor 750
NBP2-70096AF750
Allophycocyanin
NBP2-70096APC
Biotin
NBP2-70096B
CoraFluor 1
NBP2-70096CL1
DyLight 350
NBP2-70096UV
DyLight 405
NBP2-70096V
DyLight 488
NBP2-70096G
DyLight 550
NBP2-70096R
DyLight 650
NBP2-70096C
DyLight 680
NBP2-70096FR
DyLight 755
NBP2-70096IR
FITC
NBP2-70096F
HRP
NBP2-70096H
Janelia Fluor 525
NBP2-70096JF525
Janelia Fluor 549
NBP2-70096JF549
Janelia Fluor 585
NBP2-70096JF585
Janelia Fluor 635
NBP2-70096JF635
Janelia Fluor 646
NBP2-70096JF646
Janelia Fluor 669
NBP2-70096JF669
PE
NBP2-70096PE
PerCP
NBP2-70096PCP
Unconjugated
NBP2-46495
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46495
Azide and BSA Free
NBP2-70096
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alcohol dehydrogenase 5 Antibody (OTI5G4) [DyLight 594] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 1-266 of human alcohol dehydrogenase 5 (NP_000662) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADH5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for alcohol dehydrogenase 5 Antibody (OTI5G4) [DyLight 594]

  • ADH-3
  • ADHXEC 1.1.1.1
  • alcohol dehydrogenase (class III), chi polypeptide
  • alcohol dehydrogenase 5 (class III), chi polypeptide
  • Alcohol dehydrogenase 5
  • Alcohol dehydrogenase class chi chain
  • alcohol dehydrogenase class-3
  • Alcohol dehydrogenase class-III
  • EC 1.1.1
  • EC 1.1.1.-
  • EC 1.1.1.284
  • FALDH
  • FDHGSNOR
  • formaldehyde dehydrogenase
  • Glutathione-dependent formaldehyde dehydrogenase
  • GSH-FDH
  • S-(hydroxymethyl)glutathione dehydrogenase

Background

The ADH5 gene encodes glutathione dependent formaldehyde dehydrogenase or class III alcohol dehydrogenase chi subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, retinol, ethanol and other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class III alcohol dehydrogenase is a homodimer composed of 2 chi subunits. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long chain primary alcohols and for oxidation of S hydroxymethyl glutathione, a spontaneous adduct between formaldehyde and glutathione. The enzyme is an important component of cellular metabolism for the elimination of formaldehyde, which is a potent irritant and sensitizing agent that causes rhinitis, lacrymation, contact dermatitis and pharyngitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-70096DL594
alcohol dehydrogenase 5 Antibody (OTI5G4) [DyLight 594]
Species: Hu, Mu, Rt
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Bioinformatics

Gene Symbol ADH5