Immunohistochemistry-Paraffin: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP1-33096] - Cal27 xenograft. Activin A Receptor type I antibody dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH ...read more
Immunohistochemistry-Paraffin: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP1-33096] - Mouse prostate. Activin A Receptor type I antibody dilution: 1:500. Scale bar = M um.Antigen Retrieval: Trilogy™ ...read more
Activin RIA/ALK-2/Activin Receptor Type 1 Antibody Summary
Immunogen
Recombinant protein encompassing a sequence within the center region of human Activin RIA/ALK-2/Activin Receptor Type 1. The exact sequence is proprietary.
Localization
Membrane
Predicted Species
Rat (99%), Xenopus (93%), Rhesus Macaque (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ACVR1
Purity
Antigen Affinity-purified
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57 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 3 using NBP1-33096 in the following applications:
Xenopus laevis (93%). Canine reactivity reported by customer review.
Packaging, Storage & Formulations
Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified
Alternate Names for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody
activin A receptor, type I
Activin RIA
ActivinRIA
ACTRI
ACVR1
ACVR1A
ACVRLK2
ALK2
ALK-2
FOP
SKR1
TSRI
Background
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.
Publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096) (0)
There are no publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096).
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Review for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP1-33096) (1)
31
Average Rating: 3 (Based on 1 review)
We have 1 review tested in 1 species: Canine.
Reviews using NBP1-33096:
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IHC-P
(1)
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Canine
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Images
Ratings
Applications
Species
Date
Details
3
reviewed by: Faye Doherty
IHC-P
Canine
06/24/2019
View
Summary
Application
Immunohistochemistry-Paraffin
Sample Tested
TMA tested for IHC staining
Species
Canine
Lot
40073
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