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ACOX1 Antibody

Images

 
Independent Antibodies: Immunohistochemistry-Paraffin: ACOX1 Antibody [NBP1-80950] - Staining of human gastrointestinal, kidney, liver and pancreas using Anti-ACOX1 antibody NBP1-80950 (A) shows similar protein ...read more
Immunocytochemistry/ Immunofluorescence: ACOX1 Antibody [NBP1-80950] - Staining of human cell line U-2 OS shows localization to nucleoli & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: ACOX1 Antibody [NBP1-80950] - Staining of human pancreas shows no positivity in exocrine glandular cells.
Immunohistochemistry-Paraffin: ACOX1 Antibody [NBP1-80950] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: ACOX1 Antibody [NBP1-80950] - Staining of human kidney shows moderate granular cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: ACOX1 Antibody [NBP1-80950] - Staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

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ACOX1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: AVRHQSEIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGY
Predicted Species
Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ACOX1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
ACOX1 Protein (NBP1-80950PEP)
Publications
Read Publication using NBP1-80950.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%). Reactivity reported in scientific literature (PMID: 23435261)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ACOX1 Antibody

  • ACOXEC 1.3.3.6
  • acyl-CoA oxidase 1, palmitoyl
  • acyl-CoA oxidase, straight-chain
  • acyl-Coenzyme A oxidase 1, palmitoyl
  • AOX
  • PALMCOX
  • Palmitoyl-CoA oxidase
  • peroxisomal acyl-coenzyme A oxidase 1
  • peroxisomal fatty acyl-CoA oxidase
  • SCOXMGC1198
  • Straight-chain acyl-CoA oxidase

Background

ACOX1 is encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ACOX1 Antibody (NBP1-80950)(1)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for ACOX1 Antibody (NBP1-80950) (0)

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Secondary Antibodies

 

Isotype Controls

Additional ACOX1 Products

Array NBP1-80950

Research Areas for ACOX1 Antibody (NBP1-80950)

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Blogs on ACOX1

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Bioinformatics

Gene Symbol ACOX1
Entrez
Uniprot