Aldehyde Oxidase 1/AOX1 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

AOX1 (Aldehyde oxidase 1; also AO and initially termed xanthine dehydrogenase/oxidase) is a 145‑150 kDa member of the large molybdo‑flavo family of enzymes. It is a homodimer widely expressed in cells such as hepatocytes, bronchial and intestinal epithelium and adrenal cortex. It is suggested to oxidize cyclic aldehydes to carboxylic acids and likely converts retinal to retinoic acid, gentistate aldehyde to gentisate and methylmalonate semialdehyde into methylmalonate. Human AOX1 is 1338 amino acids (aa) in length. It contains a 25 kDa N‑terminal region that possesses two Fe/S redox centers (aa 5‑162), a 40 kDa flavin‑containing domain (aa 236‑421), and an 85 kDa C‑terminal region that contains a molybdenum cofactor and substrate‑binding segment (aa 711‑1245). One isoform shows a two aa substitution for aa 354‑356. Over aa 302‑531, human AOX1 shares 82% aa identity with mouse AOX1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array AF5928

• Aldehyde Oxidase 1/AOX1 Antibodies
• Aldehyde Oxidase 1/AOX1 Lysate
• Aldehyde Oxidase 1/AOX1 Proteins