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ABCB11 Antibody (BSEP/7534) [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
BSEP/7534
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

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ABCB11 Antibody (BSEP/7534) [DyLight 650] Summary

Immunogen
Recombinant fragment (around aa600-800) of human ABCB11 protein (exact sequence is proprietary)
Localization
Membrane
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
ABCB11
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ABCB11 Antibody (BSEP/7534) [DyLight 650]

  • ABC member 16, MDR/TAP subfamily
  • ABC16
  • ATP-binding cassette sub-family B member 11
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11
  • bile salt export pump
  • BSEP
  • BSEPPFIC2
  • EC 3.6.3
  • EC 3.6.3.44
  • PFIC-2
  • PGY4
  • progressive familial intrahepatic cholestasis 2
  • sister p-glycoprotein
  • SPGPBRIC2

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional ABCB11 Products

Array NBP3-27037C

Research Areas for ABCB11 Antibody (NBP3-27037C)

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Blogs on ABCB11

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Bioinformatics

Gene Symbol ABCB11