ABCA7 Antibody

Name: ABCA7 Antibody
Brand: Novus Biologicals
SKU: NBP3-42095

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Immunohistochemistry-Paraffin: ABCA7 Antibody [NBP3-42095] - DAB staining on IHC-P; Samples: Human Spleen Tissue; Primary Ab: 20ug/ml NBP3-42095; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Product Details

Summary

Reactivity	Hu, PoSpecies Glossary
Applications	WB, ICC/IF, IHC
Clonality	Polyclonal
Host	Rabbit
Conjugate	Unconjugated
Concentration	0.5 mg/ml

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ABCA7 Antibody Summary

Immunogen	Immunized with recombinant Human ABCA7 (Uniprot#: Q8IZY2; Glu53-Leu249 (Uniprot#: Q8IZY2)
Clonality	Polyclonal
Host	Rabbit
Gene	ABCA7
Purity	Antigen and protein A Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

Immunocytochemistry/ Immunofluorescence 5-20ug/mL
Immunohistochemistry 5-20ug/mL
Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer	PBS, pH7.4, 50% glycerol
Preservative	0.02% Sodium Azide
Concentration	0.5 mg/ml
Purity	Antigen and protein A Affinity-purified

Alternate Names for ABCA7 Antibody

ABCA-SSN
ABCXATP-binding cassette sub-family A member 7
ATP-binding cassette, sub-family A (ABC1), member 7
Autoantigen SS-N
EC 2.2.1.1
EC 3.6.3
EC 3.6.3.41
FLJ40025
Macrophage ABC transporter

Background

ATP-binding cassette sub-family A member 7 (ABCA7), is a member of the ATP-binding cassette sub-family A. ABCA7 is thought to have a role in phagocytosis apoptotic cells macrophages.

ABCA-7 is highly homologous to ABCA1, and also mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. It also may mediate cholesterol efflux.

ABCA7 antibodies are useful for studies of cholesterol formation and lipid processing mechanisms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ABCA7 Antibody

NBP3-42095

Species: Hu, Po

Applications: WB, ICC/IF, IHC

Publications for ABCA7 Antibody (NBP3-42095) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

ICC/IF Video Protocol

FAQs for ABCA7 Antibody (NBP3-42095) (0)

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Secondary Antibodies

Isotype Controls

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Bioinformatics

Gene Symbol

ABCA7

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

ABCA7 Antibody

Species Glossary

Images

Product Details

Order Details

ABCA7 Antibody Summary

Applications/Dilutions

Packaging, Storage & Formulations

Alternate Names for ABCA7 Antibody

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for ABCA7 Antibody (NBP3-42095) (0)

Reviews for ABCA7 Antibody (NBP3-42095) (0)

Product General Protocols

Video Protocols

FAQs for ABCA7 Antibody (NBP3-42095) (0)

Secondary Antibodies

Isotype Controls

Additional ABCA7 Products

Research Areas for ABCA7 Antibody (NBP3-42095)

Blogs on ABCA7

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics