VE-Cadherin Antibody (BV13) - BSA Free

Images

 
Flow Cytometry: VE-Cadherin Antibody (BV13) [NBP1-43348] - Analysis using the Biotin conjugate of NBP1-43348. Staining of bEnd.3 cell line with 0.5 micrograms of Rat IgG1 k Isotype Control Biotin (blue histogram) or ...read more
Flow Cytometry: VE-Cadherin Antibody (BV13) [NBP1-43348] - Staining of bEnd.3 cell line with 0.5 ug of Rat IgG1 K Isotype Control Purified (open histogram) or 0.5 ug of AntiMouse CD144 (VE-Cadherin) Purified (filled ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IHC, IP
Clone
BV13
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
BSA Free
Concentration
0.5 mg/ml

Order Details

VE-Cadherin Antibody (BV13) - BSA Free Summary

Immunogen
The immunogen for this antibody was CD144.
Marker
Endothelial Cell Marker
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
CDH5
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry < = 1 ug/10^6 cells in 100 ul
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
Application Notes
Intravenous injection of BV13 has been shown to induce a concentration- and timedependent increase in vascular permeability in the heart and lungs.
Publications
Read Publication using
NBP1-43348 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for VE-Cadherin Antibody (BV13) - BSA Free

  • 7B4 antigen
  • 7B4
  • cadherin 5, type 2 (vascular endothelium)
  • cadherin 5, type 2, VE-cadherin (vascular epithelium)
  • Cadherin-5
  • CD144 antigen
  • CD144
  • CDH5
  • endothelial-specific cadherin
  • FLJ17376
  • Vascular endothelial cadherin
  • VECadherin
  • VE-Cadherin

Background

The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for VE-Cadherin Antibody (NBP1-43348)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ICC/IF.


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ICC/IF
(1)
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Bioinformatics

Gene Symbol CDH5
Entrez
Uniprot