Rabbit VCAM-1/CD106 ELISA Kit (Colorimetric) Summary
Standard Curve Range |
62.5 - 4000 pg/mL |
Sensitivity |
37.5 pg/mL |
Assay Type |
Sandwich-ELISA |
Inter-Assay |
%CV < 5.75 |
Intra-Assay |
%CV < 6.71 |
Spike Recovery |
91 - 108% |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
VCAM1 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Micro ELISA Plate (Dismountable) - 1 EA, Reference Standard - 2 vials, Concentrated Biotinylated Detection Ab (100X) - 120 uL, Concentrated HRP Conjugate (100X) - 120 uL, Reference Standard & Sample Diluent - 20 mL, Biotinylated Detection Ab Diluent - 14
|
Alternate Names for Rabbit VCAM-1/CD106 ELISA Kit (Colorimetric)
Background
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 ( alpha4/ beta1 integrin) and LPAM-1 ( alpha4/ beta7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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