Ubiquilin 1 Antibody

UBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-56536	Applications	Species
Wang Y, Ouyang S, Liu M et al Humoral immune response to tumor-associated antigen Ubiquilin 1 (UBQLN1) and its tumor-promoting potential in lung cancer Research Square 2022-11-08 (IHC, WB, Human) Details: WB Dilutions: 1:5000; IHC Dilutions: 1:100	IHC, WB	Human
Mohan HM, Trzeciakiewicz H, Pithadia A et al. RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control Cellular and molecular life sciences : CMLS 2022-03-05 [PMID: 35247097] (WB, Human)	WB	Human

Array NBP1-56536

• Ubiquilin 1 Antibodies
• Ubiquilin 1 Lysate
• Ubiquilin 1 Protein