Ubiquilin 1 Products

Description

Ubiquilin 1 encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	22190 Mouse 29979 Human
Uniprot	AAH39294 Human NM_013438 Human NP_444295 Human Q5T6J9 Human Q9UMX0 Human
Product By Gene ID	29979
Alternate Names	DA41FLJ90054 DSK2 hPLIC-1 PLIC1 PLIC-1UBQN Protein linking IAP with cytoskeleton 1 ubiquilin 1 ubiquilin-1 XDRP1