UBE2I/Ubc9 Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. Catalyzes the covalent attachment of ubiquitin-like protein SUMO-1 to other proteins. Forms a tight complex in association with two RAN GTPase interacting proteins, RANGAP1 and RANBP2. Interacts with E1A and E2A. Interacts with HIPK1 and HIPK2. Interacts with SIAH1 and PARP. Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using NB300-812	Applications	Species
Rousseaux MW, Revelli JP, Vazquez-Velez GE et al. Depleting Trim28 in adult mice is well tolerated and reduces levels of alpha-synuclein and tau Elife 2018-06-04 [PMID: 29863470] (WB, Human)	WB	Human
Uemura A, Taniguchi M, Matsuo Y et al. UBC9 regulates the stability of XBP1, a key transcription factor controlling the ER stress response. Cell Struct Funct. 2013-01-01 [PMID: 23470653]
Wang ZY, Qiu QQ, Seufert W et al. Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9. J Biol Chem 1996-10-04 [PMID: 8798754]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IHC-P	Human	05/03/2020	View Summary Application Immunohistochemistry-Paraffin Sample Tested Breast cancer tissue Species Human Lot can not find lot No. on my vial
Enlarge	5 reviewed by: Verified Customer	WB	Human	12/27/2019	View Summary Application Western Blot Sample Tested Hela whole cell lysate Species Human Lot can not find the lot number on the original tube
Enlarge	5 reviewed by: Verified Customer	WB	Human	10/28/2018	View Summary Application Western Blot Sample Tested RCC-1,SN12C Species Human Lot No lot number printed on the tube

Array NB300-812

• UBE2I/Ubc9 Antibodies
• UBE2I/Ubc9 ELISA Kits
• UBE2I/Ubc9 Lysates
• UBE2I/Ubc9 Proteins
• UBE2I/Ubc9 Proteins and Enzyme