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TSHR Antibody - BSA Free

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Immunohistochemistry-Paraffin: TSHR Antibody [NLS1449] - Thyroid, Follicular Carcinoma
Immunohistochemistry-Paraffin: TSH R Antibody [NLS1449] - Analysis of anti-TSH Receptor / TSHR antibody with human thyroid, follicular epithelium.
Immunohistochemistry-Paraffin: TSH R Antibody [NLS1449] - Analysis of anti-TSH Receptor / TSHR antibody with human thyroid, follicular carcinoma.
Immunohistochemistry-Paraffin: TSH R Antibody [NLS1449] - Anti-TSH Receptor / TSHR antibody IHC of human Thyroid, Papillary Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more

Product Details

Summary
Reactivity Hu, Po, Bt, Ca, Pm, Eq, Pm, Pm-Or, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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TSHR Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 19 amino acid peptide from C-terminus of human TSHR.
Epitope
C-Terminus
Specificity
Human TSHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except LHCGR (42%).
Predicted Species
Porcine (94%), Chimpanzee (94%), Orangutan (94%), Primate (94%), Equine (94%), Monkey (94%), Bat (94%), Canine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TSHR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4 - 13 ug/ml
Application Notes
.
Control
TSHR Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Gibbon (94%), Marmoset (94%), Mouse (89%), Rat (89%), Sheep (89%), Feline (89%), Bovine (89%), Hamster (89%), Panda (89%), Rabbit (89%), Opossum (89%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TSHR Antibody - BSA Free

  • CHNG1
  • LGR3
  • LGR3hTSHR-I
  • MGC75129
  • seven transmembrane helix receptor
  • thyroid stimulating hormone receptor
  • Thyroid-stimulating hormone receptor
  • thyrotropin receptor
  • thyrotropin receptor-I, hTSHR-I
  • TSH R
  • TSHR
  • TSH-R

Background

Thyrotropin Receptor, a Glycoprotein Hormone Receptor, plays a central role in controlling thyroid cell metabolism. The TSH receptor can interact with both TSH and autoantibodies against the TSH receptor (thyroid-stimulating immunoglobulins, TSI). Mutations in the receptor are the cause for hyperthyroidism such as gestational hyperthyroidism (hypersensitivity to chorionic gonadotropin) and Grave's disease (autoimmune hyperthyroidism). Multiple isoforms of the thyrotropin receptor are produced by altervative splicing. The thyrotropin receptor has been reported in adipose, adrenal, brain, eye, heart, kidney, skin, thymus, and thyroid. ESTs have been isolated from brain, placenta, and thyroid libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TSHR
Entrez
Uniprot