TSHR Products

Description

Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.

Bioinformatics

Entrez	7253 Human
Uniprot	AAI56780.1 Human NM_000369 Human P16473 Human Q96GT6 Human
Product By Gene ID	7253
Alternate Names	CHNG1 LGR3hTSHR-I MGC75129 seven transmembrane helix receptor thyroid stimulating hormone receptor Thyroid-stimulating hormone receptor thyrotropin receptor thyrotropin receptor-I, hTSHR-I TSH-R

Research Areas for TSHR

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
GPCR
Membrane Trafficking and Chaperones
Neuroscience