Could you please tell me the exact homology between the sequence used to generate the NLS1436 antibody and the bovine LHR amino acid sequence?

Name: LHR Antibody - BSA Free
Brand: Novus Biologicals
SKU: NLS1436
Rating: 4 (1 reviews)

Question

Accepted Answer

The immunogen, which is proprietary, is 19 amino acids long and shares 17 similar amino acids with the bovine LHR (http://www.uniprot.org/uniprot/Q28005#sequences) sequence (89%).

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Bv, Ca, Rt, Pm, PmSpecies Glossary
Applications	IHC
Clonality	Polyclonal
Host	Rabbit
Conjugate	Unconjugated
Format	BSA Free
Concentration	1.0 mg/ml

Description	Product can be stored undiluted at 4C for up to 1 month.
Immunogen	Synthetic 19 amino acid peptide from C-terminus of human LHR.
Epitope	C-Terminus
Localization	Secreted
Specificity	Human LHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species	Rat (95%), Primate (100%), Monkey (95%). Backed by our 100% Guarantee.
Isotype	IgG
Clonality	Polyclonal
Host	Rabbit
Gene	LHCGR
Purity	Immunogen affinity purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer	PBS
Preservative	0.1% Sodium Azide
Concentration	1.0 mg/ml
Purity	Immunogen affinity purified

Publications using NLS1436	Applications	Species
Scarlet D, Aurich C, Ille N et al. Anti-Muellerian Hormone, inhibin A, gonadotropins and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy and Burdizzo castration. Theriogenology 1905-07-08 [PMID: 27693012] (IF/IHC)	IF/IHC
Noci I, Sorbi F, Mannini L et al. LH/hCG-Receptor Expression May Have a Negative Prognostic Value in Low-Risk Endometrial Cancer. Front Oncol 2016-09-09 [PMID: 27610354]
Guler S, Asmaz E, Saricetin A et al. Effects of Calcium, Available Phosphorus and Microbial Phytase on Ovarian FSHR and LHR Expression in Laying Hens Journal of the Hellenic Veterinary Medical Society 2023-10-18
Junhua Zhou, Elena A B Azizan, Claudia P Cabrera, Fabio L Fernandes-Rosa, Sheerazed Boulkroun, Giulia Argentesi, Emily Cottrell, Laurence Amar, Xilin Wu, Sam O'Toole, Emily Goodchild, Alison Marker, Russell Senanayake, Sumedha Garg, Tobias Åkerström, Samuel Backman, Suzanne Jordan, Satyamaanasa Polubothu, Daniel M Berney, Anna Gluck, Kate E Lines, Rajesh V Thakker, Antoinette Tuthill, Caroline Joyce, Juan Pablo Kaski, Fiona E Karet Frankl, Lou A Metherell, Ada E D Teo, Mark Gurnell, Laila Parvanta, William M Drake, Eva Wozniak, David Klinzing, Jyn Ling Kuan, Zenia Tiang, Celso E Gomez Sanchez, Per Hellman, Roger S Y Foo, Charles A Mein, Veronica A Kinsler, Peyman Björklund, Helen L Storr, Maria-Christina Zennaro, Morris J Brown Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause. Nature genetics 2021-10-14 [PMID: 34385710]
Martin I, Rodrigues MMP, Fujihara CJ et al. Localization patterns of steroid and luteinizing hormone receptors in the corpus luteum of Nelore (Bos taurus indicus) cows throughout the estrous cycle. Livestock Science. 2013-08-01 (IF/IHC, Bovine)	IF/IHC	Bovine
Zwida KH, Kutzler MA. Canine splenic hemangiosarcoma cells express and activate luteinizing hormone receptors in vitro Am J Vet Res 2022-11-03 [PMID: 36327166] (ICC/IF, Canine) Details: Citation using the FITC version of this antibody.	ICC/IF	Canine
Kiefel CA, Kutzler MA Assessment of luteinizing hormone receptor expression in structural support tissues of canine hip and femorotibial joints Am. J. Vet. Res. 2020-07-01 [PMID: 32584181] (IF/IHC, Canine)	IF/IHC	Canine
Yung Y, Aviel-Ronen S, Maman E et al. Localization of Luteinizing Hormone Receptor Protein in the Human Ovary. Mol. Hum. Reprod. 2014-05-29 [PMID: 24874553] (IHC-P, Human)	IHC-P	Human

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Gene Symbol	LHCGR
Entrez	3973(Human)
Uniprot	P22888(Human)

	Verified Customer 06/22/2014
Application:	ICC
Species:	Human