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TRPM8 Antibody

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Immunohistochemistry-Paraffin: TRPM8 Antibody [NBP3-14505] - Immunohistochemistry of formalin-fixed, paraffin-embedded human pancreas carcinoma after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bt, Bv, Ca, Gp, Pm, Pm, RbSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.75 mg/ml

Order Details

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TRPM8 Antibody Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 15 amino acid peptide from internal region of human TRPM8.
Epitope
Internal
Specificity
Human TRPM8. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (100%), Rat (100%), Porcine (93%), Rabbit (93%), Bovine (93%), Guinea Pig (100%), Canine (93%), Bat (93%), Monkey (100%), Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
TRPM8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
.

Reactivity Notes

Expected reactivity based on percent sequence identity: Equine, Opossum, Turkey, Chicken, Xenopus (87%)

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.75 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRPM8 Antibody

  • CMR1
  • Long transient receptor potential channel 6
  • LTRPC6
  • LTrpC-6
  • MGC2849
  • short form of the TRPM8 cationic channel
  • transient receptor potential cation channel, subfamily M, member 8
  • Transient receptor potential p8
  • transient receptor potential subfamily M member 8
  • TRPM8
  • TRPP8
  • trp-p8
  • TRPP8transient receptor potential cation channel subfamily M member 8

Background

TRPM8 is a novel gene, trp-p8 has an expression pattern within normal human tissues that is mostly restricted to prostate epithelial cells. Trp-p8 mRNA expression is at moderate levels in normal prostate tissue and appears to be elevated in prostate cancer. Notably, trp-p8 mRNA was also expressed in a number of nonprostatic primary tumors of the breast, colon, lung and skin origin, whereas transcripts encoding trp-p8 were hardly detected or not detected in the corresponding normal human tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for TRPM8 Antibody (NBP3-14505) (0)

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Secondary Antibodies

 

Isotype Controls

Additional TRPM8 Products

Array NBP3-14505

Research Areas for TRPM8 Antibody (NBP3-14505)

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Blogs on TRPM8.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

TRPM8: The Multi-functional Ion Channel
TRPM8 is a transmembrane homo-tetramer ion channel that is activated by cold temperatures, cooling agents, and menthol stimuli. It belongs to a subgroup within the larger family of TRP cation channels (including the TRPV1 capsaicin receptor) that are ...  Read full blog post.

Touch Infographic: From Touch Receptors to the Brain
The body contains thousands of receptors and nerves which allow us to experience the sense of touch, also referred to as tactile perception. The somatosensory system allows organisms to perceive and decode a wide range of tactile stimuli to allow for ...  Read full blog post.

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Bioinformatics

Gene Symbol TRPM8