TRAF-6 Antibody

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Bovine.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 2 of 2.

Publications using NBP1-80825	Applications	Species
Kai Y, Yan W, Xiaoxia C et al Neutralizing serum amyloid a protects against sinusoidal endothelial cell damage and platelet aggregation during acetaminophen-induced liver injury Biochemical and Biophysical Research Communications 2023-01-01 [PMID: 36463757]
Huidrom LD, Dhanaji SN, Pandey S et al. Embryo-Uterine Cross-Talk: Exploration of the Immunomodulatory Mechanism in Buffalo Animals : an open access journal from MDPI 2022-11-14 [PMID: 36428366] (ICC/IF, Bovine)	ICC/IF	Bovine

Array NBP1-80825

• TRAF-6 Antibodies
• TRAF-6 ELISA Kits
• TRAF-6 Inhibitor
• TRAF-6 Lysates
• TRAF-6 Proteins