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TOR/mTOR Antibody (986935) [Unconjugated]

Name: TOR/mTOR Antibody (986935) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB15371
Price: 419 USD

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TOR was detected in immersion fixed MCF-7 human breast cancer cell line using Rat Anti-Human TOR Monoclonal Antibody (Catalog # MAB15371) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the ...read more

TOR was detected in immersion fixed paraffin-embedded sections of human squamous cell carcinoma using Rat Anti-Human TOR Monoclonal Antibody (Catalog # MAB15371) at 5 µg/mL overnight at 4 °C. Tissue was stained using ...read more

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	IHC, ICC/IF
Clone	986935
Clonality	Monoclonal
Host	Rat
Conjugate	Unconjugated

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Catalog# & Formulation	Size	Price
Carrier Free MAB15371-SP

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TOR/mTOR Antibody (986935) [Unconjugated] Summary

Immunogen	E. coli-derived recombinant human TOR Phe1720-Ala2020 Accession # P42345
Specificity	Detects human TOR in direct ELISAs.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Rat
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

Immunocytochemistry 8-25 ug/mL
Immunohistochemistry 5-25 ug/mL

Packaging, Storage & Formulations

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TOR/mTOR Antibody (986935) [Unconjugated]

EC 2.7.11.1
FK506 binding protein 12-rapamycin associated protein 1
FK506 binding protein 12-rapamycin associated protein 2
FK506-binding protein 12-rapamycin complex-associated protein 1
FKBP12-rapamycin complex-associated protein
FLJ44809
FRAP
FRAP1
FRAP1FKBP12-rapamycin complex-associated protein 1
FRAP2
Mammalian target of rapamycin
mechanistic target of rapamycin (serine/threonine kinase)
Mechanistic target of rapamycin
MTOR
RAFT1
rapamycin and FKBP12 target 1
rapamycin associated protein FRAP2
Rapamycin target protein 1
RAPT1FKBP-rapamycin associated protein
serine/threonine-protein kinase mTOR
TOR

Background

TOR, also known as FRAP1, is a member of the PI 3-kinase-related kinase (PIKK) family. It is the protein target of rapamycin, an anti-rejection drug used in transplantation and promising anti-cancer agent. TOR plays a crucial role in the control of cell growth and proliferation as a downstream target of the PI 3-kinase/Akt signal transduction pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TOR/mTOR Antibody (MAB15371) (0)

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FAQs for TOR/mTOR Antibody (MAB15371) (0)

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Secondary Antibodies

Isotype Controls

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Blogs on TOR/mTOR.

Check out the latest blog posts on TOR/mTOR.

Staufen1 Overabundance and the Consequent mTOR Hyperactivity in Amyotrophic Lateral Sclerosis, Spinocerebellar Ataxia Type 2, Alzheimer’s, Parkinson’s, and Huntington’s Diseases
Jamshed Arslan, Pharm D, PhD Neurodegenerative disorders involve loss of function and, ultimately, death of neurons. Selective neuronal vulnerability has been observed in a variety of neurodegenerative diseases. Fo... Read full blog post.

mTOR Signaling and the Tumor Microenvironment
By Yoskaly Lazo-Fernandez, PhD The mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that, as a member of two distinct intracellular protein complexes, mTORC1 and mTORC2, regulates protein ... Read full blog post.

The Many Connections Between Autophagy and Kidney Disease
By Yoskaly Lazo-Fernandez, PhD The first description of what is called today an autophagosome was given in a paper published in 1957. Its author employed electron microscopy to observe the neonatal features of mous... Read full blog post.

Thomson Reuters Predicts 2016 Nobel Prize Winners
Here at Bio-Techne we always look forward to the annual announcements of winners of the highly coveted Nobel Prize – the greatest award in science. How can you go about predicting which scientists might be in line for a life-changing phone-call fro... Read full blog post.

mTOR - a central regulator of cell metabolism
The mammalian target of rapamycin (mTOR) signaling pathway allows cells to monitor environmental signals like nutrient availability and oxygen levels. mTOR is a phosphoinositide 3-kinase (PI3K)-related protein that assembles into large protein comp... Read full blog post.

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P42345()

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

TOR/mTOR Antibody (986935) [Unconjugated]

Species Glossary

Images

Product Details

Order Details

TOR/mTOR Antibody (986935) [Unconjugated] Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for TOR/mTOR Antibody (986935) [Unconjugated]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for TOR/mTOR Antibody (MAB15371) (0)

Reviews for TOR/mTOR Antibody (MAB15371) (0)

FAQs for TOR/mTOR Antibody (MAB15371) (0)

Secondary Antibodies

Isotype Controls

Additional TOR/mTOR Products

Blogs on TOR/mTOR.

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics