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TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

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Flow Cytometry: TNF RI/TNFRSF1A Antibody (H398) - Azide Free [NBP2-37724] - Analysis (surface staining) of CD120a in human peripheral blood with anti-human CD120a (H398) purified, GAM-APC.
Surface staining pattern of human peripheral whole blood stained using anti-human CD120a (H398) purified antibody (low endotoxin, concentration in sample 3 ug/ml) GAM APC.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Func, IHC, IP, B/N, CyTOF-ready
Clone
H398
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

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TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free Summary

Immunogen
Recombinant full length human CD120a.
Specificity
Antibody recognizes the extracellular domain of CD120a, a 55 kDa receptor for tumor necrosis factor. Antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF1A
Purity
Protein A purified
Endotoxin Note
Endotoxin level is less than 0.01 EU/ug of the protein
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Block/Neutralize
  • CyTOF-ready
  • Flow Cytometry 1-4 ug/ml
  • Functional
  • Immunohistochemistry
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
This antibody is Cytof ready.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4), 0.2 um filter sterilized
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for TNF RI/TNFRSF1A Antibody (H398) - Azide and BSA Free

  • CD120a antigen
  • CD120a
  • FPF
  • p55
  • p55-R
  • p60
  • TNF RI
  • TNFARMGC19588
  • TNF-R
  • TNF-R1
  • TNFR1TBP1
  • TNFR55
  • TNF-R55
  • TNFR60
  • TNFRI
  • TNF-RI
  • TNF-R-I
  • TNFR-I
  • TNFRSF1A
  • tumor necrosis factor binding protein 1
  • Tumor necrosis factor receptor 1
  • tumor necrosis factor receptor 1A isoform beta
  • tumor necrosis factor receptor superfamily member 1A
  • tumor necrosis factor receptor superfamily, member 1A
  • tumor necrosis factor receptor type 1
  • Tumor necrosis factor receptor type I
  • tumor necrosis factor-alpha receptor

Background

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF1A