TMEM43 Antibody

TMEM43 belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq].

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 applications: IF/IHC, PLA, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-84132	Applications	Species
Gry M, Oksvold P, Ponten F et al. Tissue-specific protein expression in human cells, tissues and organs. J Proteomics Bioinform 2010-01-01
Jang MW, Kim TY, Sharma K Et al. A Deafness Associated Protein TMEM43 Interacts with KCNK3 (TASK-1) Two-pore Domain K+ (K2P) Channel in the Cochlea Experimental neurobiology 2021-10-31 [PMID: 34737237] (WB, PLA, IF/IHC)	WB, PLA, IF/IHC
Christensen AH, Andersen CB, Tybjaerg-Hansen A et al. Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy. Clin Genet 2011-09-01 [PMID: 21214875]

Array NBP1-84132

• TMEM43 Antibodies
• TMEM43 Lysate
• TMEM43 Protein