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Desmoplakin Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining in human skin and skeletal muscle tissues using anti-DSP antibody. Corresponding DSP RNA-seq data are presented ...read more
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining of human skin shows moderate cytoplasmic positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] -Staining of human lymph node shows no cytoplasmic positivity in germinal center cells.

Product Details

Summary
Reactivity Hu, Ca, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Desmoplakin Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: NHNKVIETNRENDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKDMLANFRGSEKYCYLQNEVF
Predicted Species
Mouse (92%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DSP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence Reported in scientific literature (PMID:34983311)
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Desmoplakin Recombinant Protein Antigen (NBP2-48836PEP)
Publications
Read Publications using
NBP2-48836 in the following applications:

Reactivity Notes

Use in Canine reported in scientific literature (PMID:34983311).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Desmoplakin Antibody

  • 250/210 kDa paraneoplastic pemphigus antigen
  • DCWHKTA
  • desmoplakin (DPI, DPII)
  • desmoplakin I
  • desmoplakin II
  • Desmoplakin
  • DP
  • DPI
  • DPII
  • DSP
  • KPPS2
  • PPKS2

Background

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Desmoplakin Antibody (NBP2-48836)(2)

We have publications tested in 2 confirmed species: Mouse, Canine.

We have publications tested in 2 applications: ICC/IF, IF/IHC.


Filter By Application
ICC/IF
(1)
IF/IHC
(1)
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Filter By Species
Mouse
(1)
Canine
(1)
All Species

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol DSP