Orthogonal Strategies: Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining in human skin and skeletal muscle tissues using anti-DSP antibody. Corresponding DSP RNA-seq data are presented ...read more
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] - Staining of human skin shows moderate cytoplasmic positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-48836] -Staining of human lymph node shows no cytoplasmic positivity in germinal center cells.
This antibody was developed against a recombinant protein corresponding to amino acids: NHNKVIETNRENDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKDMLANFRGSEKYCYLQNEVF
Predicted Species
Mouse (92%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DSP
Purity
Immunogen affinity purified
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Use in Canine reported in scientific literature (PMID:34983311).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Desmoplakin Antibody
250/210 kDa paraneoplastic pemphigus antigen
DCWHKTA
desmoplakin (DPI, DPII)
desmoplakin I
desmoplakin II
Desmoplakin
DP
DPI
DPII
DSP
KPPS2
PPKS2
Background
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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