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Thyroid Peroxidase Antibody (SR1030)

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Western Blot: Thyroid Peroxidase Antibody (SR1030) [NBP3-21810] - Western blot analysis using NBP3-21810 in Human thyroid lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clone
SR1030
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Thyroid Peroxidase Antibody (SR1030) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Thyroid Peroxidase (Uniprot #: P07202)
Specificity
Detects endogenous levels of total Thyroid Peroxidase
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
TPO
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:500
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:5000
Theoretical MW
103 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Thyroid Peroxidase Antibody (SR1030)

  • EC 1.11.1
  • MSA
  • TDH2A
  • thyroid microsomal antigen
  • thyroid peroxidase
  • thyroperoxidase
  • TPXEC 1.11.1.8

Background

Thyroid Peroxidase encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TPO