TERF2IP Antibody (RAP1 5G7/1) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in budding yeast. However, human Rap1 (hRap1) is an ortholog of the yeast telomeric protein, scRap1p. hRap1 is a homodimer, has three conserved sequence motifs in common with scRap1, is located at telomeres, and plays a role in telomere length regulation. Although scRap1 binds telomeric DNA directly, hRap1 is recruited to telomeres by TRF2 and binds it with its C-terminus, rather than directly binding DNA.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NB120-14403JF646

• TERF2IP Antibodies
• TERF2IP ELISA Kits
• TERF2IP Lysate
• TERF2IP Proteins