TBX5 Antibody

TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, IF/IHC, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP1-83237	Applications	Species
Yamasaki S, Kuwahara A, Kishino A et al. Addition of Chk1 inhibitor and BMP4 cooperatively promotes retinal tissue formation in self-organizing human pluripotent stem cell differentiation culture Regenerative Therapy 2022-03-01 [PMID: 35059477] (IF/IHC, Human)	IF/IHC	Human
Sun W, Ramirez S, Spiller K et al. Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye Hum Mol Genet 2020-10-19 [PMID: 33075808]
Kokkinopoulos I, Ishida H, Saba R et al. Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo. PLoS One 2015-01-01 [PMID: 26469858] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Lian X, Zhang J, Azarin SM et al. Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/-beta-catenin signaling under fully defined conditions. Nat Protoc 2013-01-01 [PMID: 23257984]

Array NBP1-83237

• TBX5 Antibodies
• TBX5 Lysates
• TBX5 Proteins