Tafazzin/TAZ Antibody

The tafazzin protein plays a key role in Barth syndrome. Barth syndrome appears to be a disease of the mitochondria. Tafazzin protrudes into the intermembrane space from both the outer and inner membranes. The tafazzin protein may be associated with cardiolipin, the signature lipid of mitochondria, which has been implicated in other diseases, including those of the heart. Tafazzin may be important in repairing lipids, including cardiolipin, but it is not determined. Tafazzin's association with both the outer membrane and the inner membrane is consistent with its ability to modify a membrane component such as cardiolipin. This antibody is expected to recognise isoforms 1to 4 (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB600-811	Applications	Species
Brandner K, Mick DU, Frazier AE et al. Taz1, an outer mitochondrial membrane protein, affects stability and assemblyof inner membrane protein complexes: implications for Barth Syndrome. Mol Biol Cell 2005-11-01 [PMID: 16135531]

Array NB600-811

• Tafazzin/TAZ Antibodies
• Tafazzin/TAZ ELISA Kits
• Tafazzin/TAZ Lysate
• Tafazzin/TAZ Proteins