Tafazzin/TAZ Antibody (1B10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternative transcripts encoding additional isoforms have been described but the full-length nature of these transcripts is not known.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 6 of 6.

Publications using H00006901-M12	Applications	Species
Val Fajardo, John Mikhaeil, Cameron Leveille et al. Cardiolipin content, linoleic acid composition, and tafazzin expression in response to skeletal muscle overload and unload stimuli. Sci Rep. [PMID: 28515468] (WB, Mouse)	WB	Mouse
Li J, Fang L, Yu W, Wang Y. MicroRNA-125b suppresses the migration and invasion of hepatocellular carcinoma cells by targeting transcriptional coactivator with PDZ-binding motif Oncology Letters. 2015-01-01 [PMID: 25789078] (WB, Human) Details: Tafazzin/TAZ antibody was used at 1:1500 dilution with 2 hour incubation at 37C for WB application on lysates of SK-Hep-1 cells transfected with si-TAZ or TAZ plasmid lacking 3'UTR along with miR-125b (Figure 4A), and on cells overexpressing TAZ and/or miR-125b (Figure 4B). WB was also performed on SK-Hep-1 cells overexpressing miR-125b and Huh7 cells treated or not with miR-125b inhibitor (Figure 3).	WB	Human
Raghunathan VK, Dreier B, Morgan JT et al. Involvement of YAP, TAZ and HSP90 in Contact Guidance and Intercellular Junction Formation in Corneal Epithelial Cells. PLoS One. 2014-10-07 [PMID: 25290150]
Thomasy SM, Morgan JT, Wood JA et al. Substratum stiffness and latrunculin B modulate the gene expression of the mechanotransducers YAP and TAZ in human trabecular meshwork cells. Exp Eye Res. 2013-05-29 [PMID: 23727052]
Raghunathan VK, Morgan JT, Dreier B et al. Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ. Invest Ophthalmol Vis Sci. 2013-01-14 [PMID: 23258147]
Elkes M The temporal relationship between cardiolipin biosynthesis and remodeling enzymes and cardiolipin content during unloading atrophy in mouse soleus Thesis 2022-01-01

Images	Ratings	Applications	Species	Date	Details
Enlarge	3 reviewed by: Verified Customer	WB	Mouse	08/26/2016	View Summary Application Western Blot Sample Tested Soleus Species Mouse

Array H00006901-M12

• Tafazzin/TAZ Antibodies
• Tafazzin/TAZ ELISA Kits
• Tafazzin/TAZ Lysate
• Tafazzin/TAZ Proteins