![SUMO1 Antibody (SPM571) [mFluor Violet 610 SE] [NBP2-34805MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.](http://images.novusbio.com/fullsize/nbp2-34805mfv610_mouse-sumo1-mab-spm571-mfluor-violet-610-se-6720238545231.png "SUMO1 Antibody (SPM571) [mFluor Violet 610 SE] [NBP2-34805MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.")
| Reactivity | HuSpecies Glossary |
| Applications | WB, Flow, ICC/IF, IHC, CyTOF-ready |
| Clone | SPM571 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | mFluor Violet 610 SE |
| Immunogen | Recombinant human SUMO1 protein (Uniprot: P63165) |
| Localization | Predominantly nuclear with some cytoplasmic |
| Specificity | This monoclonal antibody is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. |
| Isotype | IgG1 Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | SUMO1 |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
![SUMO1 Antibody (SPM571) [mFluor Violet 610 SE]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "SUMO1 Antibody (SPM571) [mFluor Violet 610 SE]")
Secondary Antibodies |
Isotype Controls |
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| Gene Symbol | SUMO1 |
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