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SPNS1 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: SPNS1 Antibody [NBP1-92440] - Staining in human lung and pancreas tissues using NBP1-92440 antibody. Corresponding SPNS1 RNA-seq data are presented for the ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: SPNS1 Antibody [NBP1-92440] - Staining of human lung, pancreas, placenta and testis using Anti-SPNS1 antibody NBP1-92440 (A) shows similar protein ...read more
Immunohistochemistry-Paraffin: SPNS1 Antibody [NBP1-92440] - Staining of human lung shows strong granular cytoplasmic positivity in macrophages.
Immunohistochemistry-Paraffin: SPNS1 Antibody [NBP1-92440] - Staining of human pancreas shows very weak positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: SPNS1 Antibody [NBP1-92440] - Staining of human placenta shows strong granular cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: SPNS1 Antibody [NBP1-92440] - Staining of human testis shows weak granular cytoplasmic positivity in Leydig cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SPNS1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPNS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SPNS1 Protein (NBP1-92440PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (84%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SPNS1 Antibody

  • FLJ38358
  • HSpin1Spinster-like protein 1
  • LAT
  • PP2030
  • protein spinster homolog 1
  • SPIN1nrs
  • SPINL
  • spinster homolog 1 (Drosophila)

Background

SPNS1 is a human ortholog of the Drosophila melanogaster spin gene. Many orthologs have been identified in a number of species from nematodes to humans. In drosophila the Spin protein may function in mediating apoptotic signals conveyed from follicle cells to nurse cells or from glia to neurons. The accumulation of lipofuscin-like materials in spin mutant neurons further implies the possible function of the spin gene in regulating lysosomal turnover in nerve cells. SPNS1 may be involved in necrotic or autophagic cell death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SPNS1