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SOX7 Antibody [Unconjugated]

 (17 Publications)
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Biotin
BAF2766
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF2766-SP
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SOX7 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human SOX7
Ser249-Ala345
Accession # Q9BT81
Specificity
Detects human SOX7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human SOX1, -2, -3, -9, -10, and -17 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SOX7
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF2766 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX7 Antibody [Unconjugated]

  • MGC10895
  • SOX7 transcription factor
  • SOX7
  • SRY (sex determining region Y)-box 7
  • transcription factor SOX-7

Background

SOX7 belongs to the Sox (SRY-like HMG-box gene) family of transcription factors with diverse roles in development. SOX7 has been suggested to play a crucial role in parietal endoderm differentiation. SOX7 is expressed in many embryonic and adult tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SOX7 Antibody (AF2766)(17)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 6 applications: Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P, Western Blot.


Filter By Application
Flow Cytometry
(1)
ICC
(4)
IHC
(1)
IHC-Fr
(1)
IHC-P
(1)
Western Blot
(2)
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Human
(4)
Mouse
(5)
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Showing Publications 1 - 10 of 17. Show All 17 Publications.
Publications using AF2766 Applications Species
Ivy K N Chiang, Matthew S Graus, Nils Kirschnick, Tara Davidson, Winnie Luu, Richard Harwood et al. The blood vasculature instructs lymphatic patterning in a SOX7‐dependent manner The EMBO Journal 2023-03-01 [PMID: 36715213]
Ayaka Yanagida, Elena Corujo-Simon, Christopher K. Revell, Preeti Sahu, Giuliano G. Stirparo, Irene M. Aspalter et al. Cell surface fluctuations regulate early embryonic lineage sorting Cell 2022-03-03 [PMID: 35196500]
N Hong, E Zhang, H Xie, L Jin, Q Zhang, Y Lu, AF Chen, Y Yu, B Zhou, S Chen, Y Yu, K Sun The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling Cell Death & Disease, 2021-04-12;12(4):393. 2021-04-12 [PMID: 33846290] (Flow Cytometry, ICC, Human) Flow Cytometry, ICC Human
J Klomp, J Hyun, J Klomp, K Pajcini, J Rehman, AB Malik Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells J. Biol. Chem., 2020-02-18;0(0):. 2020-02-18 [PMID: 32071080] (Western Blot, Human) Western Blot Human
Claire S. Simon, Lu Zhang, Tao Wu, Weibin Cai, Nestor Saiz, Sonja Nowotschin et al. A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse Biology Open 2018-12-15 [PMID: 30530745]
Wei Peng, Lizheng Guo, Ruoyi Tang, Xiuju Liu, Rui Jin, Jin‐Tang Dong et al. Sox7 negatively regulates prostate‐specific membrane antigen (PSMA) expression through PSMA‐enhancer The Prostate 2019-03-01 [PMID: 30488457]
Yumeng Zhang, Daniel B. Stovall, Meimei Wan, Qiang Zhang, Jeff W. Chou, Dangdang Li et al. SOX7 Target Genes and Their Contribution to Its Tumor Suppressive Function International Journal of Molecular Sciences 2018-05-14 [PMID: 29757932]
IK Kim, K Kim, E Lee, DS Oh, CS Park, S Park, JM Yang, JH Kim, HS Kim, DT Shima, JH Kim, SH Hong, YH Cho, YH Kim, JB Park, GY Koh, YS Ju, HK Lee, S Lee, I Kim Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality J. Exp. Med., 2018-02-14;0(0):. 2018-02-14 [PMID: 29444818] (IHC-P, Mouse) IHC-P Mouse
AJ Lilly, A Mazan, DA Scott, G Lacaud, V Kouskoff SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development Mech. Dev., 2017-05-31;0(0):. 2017-05-31 [PMID: 28577909] (IHC, Mouse) IHC Mouse
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos Sci Rep, 2016-12-19;6(0):39457. 2016-12-19 [PMID: 27991575] (ICC, Mouse) ICC Mouse
Show All 17 Publications.

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Bioinformatics

Gene Symbol SOX7
Uniprot