Independent Antibodies: Western Blot: SMCX Antibody [NB100-55328] - Detection of Human JARID1C on HeLa whole cell lysate using NB100-55328. JARID1C was also immunoprecipitated by rabbit anti-JARID1C antibody ...read more
The immunogen recognized by this antibody maps to a region between residue 1510 and the C-terminus (residue 1560) of human Jumonji, AT rich interactive domain 1C using the numbering given in entry NP_004178.2 (GeneID 8242).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM5C
Purity
Immunogen affinity purified
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Jumonji, AT rich interactive domain 1C (RBP2-like)
jumonji, AT rich interactive domain 1C
Jumonji/ARID domain-containing protein 1C
KDM5C
lysine (K)-specific demethylase 5C
MRXSJ
Protein SmcX
Protein Xe169
Smcx homolog, X chromosome
SMCX
SMCXselected cDNA on X
Smcy homolog, X-linked (mouse)
Smcy homolog, X-linked
XE169
XE169JmjC domain-containing protein SMCX
Background
This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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