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SDHB Antibody (SDHB/6697R) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
SDHB/6697R
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

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SDHB Antibody (SDHB/6697R) [DyLight 550] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Synthetic peptide corresponding to residues in human SDHB was used as an immunogen. (Uniprot: P21912 )
Localization
Cytoplasm, Mitochondria
Marker
Pheochromocytoma Marker
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
SDHB
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SDHB Antibody (SDHB/6697R) [DyLight 550]

  • EC 1.3.5.1
  • FLJ92337
  • IP
  • Iron-sulfur subunit of complex II
  • PGL4
  • SDH
  • SDH1
  • SDH2
  • SDHIP
  • succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Background

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SDHB