S1P1/EDG-1 Antibody (218713) [Allophycocyanin] Summary
Additional Information |
Clone 218713 was used by HLDA to establish CD designation |
Immunogen |
NS0 mouse myeloma cell line transfected with human S1P1/EDG‑1 Met1-Ser382 Accession # P21453 |
Specificity |
Detects human S1P1/EDG‑1 by flow cytometry. |
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
S1PR1 |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 10 uL/10^6 cells
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Publications |
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Packaging, Storage & Formulations
Storage |
Protect from light. Do not freeze.- 12 months from date of receipt, 2 to 8 °C as supplied.
|
Buffer |
Supplied in a saline solution containing BSA and Sodium Azide. |
Preservative |
Sodium Azide |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for S1P1/EDG-1 Antibody (218713) [Allophycocyanin]
Background
S1P1, also known as EDG-1, is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1-phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for S1P1/EDG-1 Antibody (FAB2016A)(3)
Showing Publications 1 -
3 of 3.
Publications using FAB2016A |
Applications |
Species |
Janneh AH, Kassir MF, Atilgan FC et al. Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis Cell Reports 2022-12-06 [PMID: 36476873] |
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Janneh AH, Kassir MF, Atilgan FC et al. Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis Cell Reports 2022-12-06 [PMID: 36476873] |
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Anchana Rathinasamy, Christoph Domschke, Yingzi Ge, Hans-Henning Böhm, Steffen Dettling, David Jansen et al. Tumor specific regulatory T cells in the bone marrow of breast cancer patients selectively upregulate the emigration receptor S1P1 Cancer Immunology, Immunotherapy 2017-05-01 [PMID: 28224210] |
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FAQs for S1P1/EDG-1 Antibody (FAB2016A) (0)
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