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S1P1/EDG-1 Antibody (218713) [Phycoerythrin]

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CHO Chinese hamster ovary cell line transfected with either (A) human S1P1/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P1/EDG-1 PE-conjugated Monoclonal Antibody (Catalog # FAB2016P). Quadrant markers were set based on control antibody staining (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.
CHO Chinese hamster ovary cell line transfected with either (A) human S1P1/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P1/EDG-1 PE-conjugated Monoclonal Antibody (Catalog # ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
218713
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB2016U-100UG
Alexa Fluor 405
FAB2016V-100UG
Alexa Fluor 488
FAB2016G-100UG
Alexa Fluor 532
FAB2016X
Alexa Fluor 594
FAB2016T-100UG
Alexa Fluor 647
FAB2016R-100UG
Alexa Fluor 700
FAB2016N
Alexa Fluor 750
FAB2016S-100UG
Allophycocyanin
FAB2016A
Allophycocyanin/Cy7
FAB2016APCCY7
Biotin
FAB2016B
CoraFluor 1
FAB2016CL1
DyLight 350
FAB2016D
DyLight 405
FAB2016E
DyLight 488
FAB2016K
DyLight 550
FAB2016L
DyLight 594
FAB2016M
DyLight 650
FAB2016W
DyLight 680
FAB2016Y
DyLight 755
FAB2016Z
FITC
FAB2016F
HRP
FAB2016H
Janelia Fluor 525
FAB2016JF525
Janelia Fluor 549
FAB2016I
Janelia Fluor 585
FAB2016JF585
Janelia Fluor 635
FAB2016JF635
Janelia Fluor 646
FAB2016J
Janelia Fluor 669
FAB2016JF669
PE/Atto594
FAB2016PEATT594
PE/Cy5.5
FAB2016PECY55
PE/Cy7
FAB2016PECY7
PerCP
FAB2016C
Unconjugated
MAB2016-100
mFluor Violet 450 SE
FAB2016MFV450
mFluor Violet 500 SE
FAB2016MFV500
mFluor Violet 610 SE
FAB2016MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2016-100
Carrier Free
FAB2016A
Carrier Free
FAB2016N
Carrier Free
MAB2016-SP
Carrier Free
MAB2016-500
Carrier Free
MAB2016-100
Carrier Free
FAB2016G-100UG
Carrier Free
FAB2016V-100UG
Carrier Free
FAB2016U-100UG
Carrier Free
FAB2016T-100UG
Carrier Free
FAB2016S-100UG
Carrier Free
FAB2016R-100UG
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S1P1/EDG-1 Antibody (218713) [Phycoerythrin] Summary

Additional Information
Clone 218713 was used by HLDA to establish CD designation
Immunogen
NS0 mouse myeloma cell line transfected with human S1P1/EDG‑1
Met1-Ser382
Accession # P21453
Specificity
Detects human S1P1/EDG‑1 by flow cytometry.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
S1PR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB2016P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S1P1/EDG-1 Antibody (218713) [Phycoerythrin]

  • CD363 antigen
  • CD363
  • CHEDG1
  • D1S3362
  • EDG1
  • EDG-1
  • EDG1edg-1
  • Endothelial differentiation G-protein coupled receptor 1
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
  • FLJ58121
  • S1P receptor 1
  • S1P receptor Edg-1
  • S1P1
  • S1P1ECGF1
  • S1PR1
  • sphingosine 1-phosphate receptor 1
  • sphingosine 1-phosphate receptor EDG1
  • Sphingosine 1-phosphate receptor Edg-1
  • sphingosine-1-phosphate receptor 1

Background

S1P1, also known as EDG-1, is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1-phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for S1P1/EDG-1 Antibody (FAB2016P)(5)

We have publications tested in 2 confirmed species: Human, Hamster.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(4)
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Human
(3)
Hamster
(1)
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Showing Publications 1 - 5 of 5.
Publications using FAB2016P Applications Species
J Jin, N Xue, Y Liu, R Fu, M Wang, M Ji, F Lai, J Hu, X Wang, Q Xiao, X Zhang, D Yin, L Bai, X Chen, S Rao A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models Acta Pharm Sin B, 2019-11-14;10(2):276-288. 2019-11-14 [PMID: 32082973] (Flow Cytometry, Hamster) Flow Cytometry Hamster
King Faisal Yambire, Lorena Fernandez-Mosquera, Robert Steinfeld, Christiane Mühle, Elina Ikonen, Ira Milosevic et al. Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases eLife 2/18/2019 [PMID: 30775969]
P Annunziata, C Cioni, G Masi, M Tassi, G Marotta, S Severi Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients Sci Rep, 2018-10-18;8(1):15371. 2018-10-18 [PMID: 30337577] (Flow Cytometry, Human) Flow Cytometry Human
Borge M, Remes Lenicov F, Nannini P, de los Rios Alicandu M, Podaza E, Ceballos A, Fernandez Grecco H, Cabrejo M, Bezares R, Morande P, Oppezzo P, Giordano M, Gamberale R The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406. J Immunol, 2014-08-15;193(6):3165-74. 2014-08-15 [PMID: 25127862] (Flow Cytometry, Human) Flow Cytometry Human
Llinas L, Lazaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Immunol. Lett., 2010-10-15;134(2):113-21. 2010-10-15 [PMID: 20951740] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol S1PR1
Uniprot