Novus Biologicals products are now on bio-techne.com

RNase L Antibody

Images

 
Immunohistochemistry-Paraffin: RNase L Antibody [NBP1-87230] - Staining of human small intestine shows weak cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

RNase L Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: HGAKEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIYLGFYEKQEVAVKTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVHRGEDVENEEDEFARNVLSSI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RNASEL
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
RNase L Recombinant Protein Antigen (NBP1-87230PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for RNase L Antibody

  • 2-5A-dependent ribonuclease
  • 2-5A-dependent RNase
  • 2'-5'-oligoisoadenylate synthetase-dependent
  • EC 3.1.26.-
  • HPC1
  • interferon-induced 2-5A-dependent RNase
  • MGC104972
  • MGC133329
  • PRCA1
  • prostate cancer 1
  • Ribonuclease 4
  • ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent)
  • Ribonuclease L
  • RNase L
  • RNS4DKFZp781D08126

Background

RNase L is a virally induced endoribonuclease that is also the terminal factor of the anti-viral action of interferon. Activation of RNase L results in inhibition of viral proliferation through total RNA degradation. Activation of RNase L has also been determined to degrade RNA, thus, initiating a cellular stress response, inducing apoptosis. Since mutations in RNase L relate to an increased incidence of prostate cancer, the activation of RNase L is thought to function in counteracting prostate cancer, via apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-77266
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
AF8519
Species: Hu, Mu, Rt
Applications: Simple Western, WB
NBP2-75930
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
AF5550
Species: Mu, Rt
Applications: WB
NB400-116
Species: Hu, Pm
Applications: ICC/IF, IP, WB
NBP1-00092
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, PLA, WB
NBP1-84620
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
8499-IF
Species: Hu
Applications: BA
NBP1-32905
Species: Bv, Hu, Pm, Rb
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
NB100-2323
Species: Dr, Gt, SyHa, Hu, Ma, Pm, Mu, Po, Pm, Rb, Rt
Applications: ChIP, ELISA, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vitro, KD, Simple Western, WB
AF4859
Species: Hu
Applications: WB
NBP3-41911
Species: Hu, Po
Applications: ICC/IF, IHC, WB
M6000B
Species: Mu
Applications: ELISA
MAB17761
Species: Hu, Mu, Rt
Applications: ICC, WB
NB110-1244
Species: Hu, Mu, Pm
Applications: Flow, IHC, IHC-P, PEP-ELISA
DKK300
Species: Hu
Applications: ELISA
NBP1-87230
Species: Hu
Applications: IHC

Publications for RNase L Antibody (NBP1-87230) (0)

There are no publications for RNase L Antibody (NBP1-87230).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for RNase L Antibody (NBP1-87230) (0)

There are no reviews for RNase L Antibody (NBP1-87230). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for RNase L Antibody (NBP1-87230) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our RNase L Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol RNASEL