Recombinant Mouse Wnt-3a Protein, CF

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes (1). Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta -catenin levels (2). As intracellular beta -catenin levels rise, beta -catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes (3). Endo-IWR 1 (Catalog # 3532, # PSM1324) is a cell-permeant small molecule inhibitor of Axin turnover that suppresses Wnt signal transduction by stabilizing the beta -catenin destruction complex (4). Wnt-3a is a 44 kDa secreted hydrophobic glycoprotein containing a conserved pattern of 24 cysteine residues (5). Wnt-3a has two N-linked glycosylation sites (Asn 87, Asn 298), and Ser 209 is modified with palmitoleic acid (6). Glycosylation and acylation are essential for efficient Wnt secretion and biological activity, respectively (6, 7). Mouse Wnt-3a shares 96% amino acid (aa) identity with human Wnt-3a, and 97% with bovine and canine Wnt-3a. The rat Wnt-3a precursor shares 100% aa identity with mouse Wnt-3a aa 63-352 (8), and also shares 87% aa identity with Wnt3. During embryonic development, Wnt-3a is necessary for proper development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation (9-12). Wnt-3a also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells (13-15).

We have publications tested in 6 confirmed species: Human, Mouse, Rat, Chicken, Rabbit, Transgenic Mouse.

We have publications tested in 6 applications: Binding Assay, Bioassay, Cell Culture, In Vivo, Organoid Culture, Receptor Binding Assay.

Showing Publications 1 - 10 of 192. Show All 192 Publications. Collapse Publications.

Publications using 1324-WN/CF	Applications	Species
Ortabozkoyun, H;Huang, PY;Cho, H;Tsirigos, A;Mazzoni, E;Reinberg, D; Novel Chromatin Insulating Activities Uncovered upon Eliminating Known Insulators in vivo bioRxiv : the preprint server for biology 2023-04-25 [PMID: 37162865] (Bioassay, Mouse)	Bioassay	Mouse
M Nomura, Y Yokoyama, D Yoshimura, Y Minagawa, A Yamamoto, Y Tanaka, N Sekiguchi, D Marukawa, M Ichihara, H Itakura, K Matsumoto, Y Morimoto, H Tomihara, A Inoue, T Ogino, N Miyoshi, H Takahashi, H Takahashi, M Uemura, S Kobayashi, T Mizushima, T Anada, M Mori, Y Doki, M Tanaka, H Eguchi, H Yamamoto Simple Detection and Culture of Circulating Tumor Cells from Colorectal Cancer Patients Using Poly(2-Methoxyethyl Acrylate)-Coated Plates International Journal of Molecular Sciences, 2023-02-16;24(4):. 2023-02-16 [PMID: 36835361] (Bioassay, Human)	Bioassay	Human
YF Wong, Y Kumar, M Proks, JAR Herrera, MM Rothová, RS Monteiro, S Pozzi, RE Jennings, NA Hanley, WA Bickmore, JM Brickman Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation Nature Cell Biology, 2023-01-23;0(0):. 2023-01-23 [PMID: 36690849] (Bioassay, Human)	Bioassay	Human
LA Dada, LC Welch, ND Magnani, Z Ren, H Han, PL Brazee, D Celli, AS Flozak, A Weng, MM Herrerias, V Kryvenko, I Vadász, CE Runyan, H Abdala-Val, M Shigemura, SM Casalino-M, AV Misharin, GRS Budinger, CJ Gottardi, JI Sznajder Hypercapnia alters stromal-derived Wnt production limiting beta-catenin signaling and proliferation in alveolar type 2 cells JCI Insight, 2023-02-22;0(0):. 2023-02-22 [PMID: 36626234] (Bioassay, Mouse)	Bioassay	Mouse
Y Niu, CA Ferreira A, X Li, E Kamali, O Haagen Nie, C Storgaard, M Frödin Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select Nature Genetics, 2022-12-05;54(12):1983-1993. 2022-12-05 [PMID: 36471068] (Bioassay, Human)	Bioassay	Human
N Pentinmikk, R Lozano, S Scharaw, S Andersson, JI Englund, D Castillo-A, A Gallagher, M Broberg, KY Song, A Sola Carva, AT Speidel, M Sundstrom, N Allbritton, MM Stevens, OD Klein, A Teixeira, P Katajisto Cellular shape reinforces niche to stem cell signaling in the small intestine Science Advances, 2022-10-14;8(41):eabm1847. 2022-10-14 [PMID: 36240269] (Bioassay, Mouse)	Bioassay	Mouse
H Marei, WK Tsai, YS Kee, K Ruiz, J He, C Cox, T Sun, S Penikalapa, P Dwivedi, M Choi, D Kan, P Saenz-Lope, K Dorighi, P Zhang, YT Kschonsak, N Kljavin, D Amin, I Kim, AG Mancini, T Nguyen, C Wang, E Janezic, A Doan, E Mai, H Xi, C Gu, M Heinlein, B Biehs, J Wu, I Lehoux, S Harris, L Comps-Agra, D Seshasayee, FJ de Sauvage, M Grimmer, J Li, NJ Agard, F de Sousa E Antibody targeting of E3 ubiquitin ligases for receptor degradation Nature, 2022-09-21;610(7930):182-189. 2022-09-21 [PMID: 36131013] (Bioassay, Human)	Bioassay	Human
G Pizzolato, L Moparthi, S Söderholm, C Cantù, S Koch The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes Journal of Cell Science, 2022-10-10;0(0):. 2022-10-10 [PMID: 36124643] (Cell Culture, Human)	Cell Culture	Human
Z Wang, R Fan, A Russo, FM Cernilogar, A Nuber, S Schirge, I Shcherbako, I Dzhilyanov, E Ugur, T Anton, L Richter, H Leonhardt, H Lickert, G Schotta Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm Nature Communications, 2022-09-19;13(1):5447. 2022-09-19 [PMID: 36123357] (Bioassay, Mouse)	Bioassay	Mouse
G Liu, J Chen, X Wang, Y Liu, Y Ma, X Tu Functionalized 3D-Printed ST2/Gelatin Methacryloyl/Polcaprolactone Scaffolds for Enhancing Bone Regeneration with Vascularization International Journal of Molecular Sciences, 2022-07-28;23(15):. 2022-07-28 [PMID: 35955478] (Cell Culture, Mouse)	Cell Culture	Mouse
Y Mita, H Zhu, Y Furuichi, H Hamaguchi, Y Manabe, NL Fujii R-spondin3 is a myokine that differentiates myoblasts to type I fibres Scientific Reports, 2022-07-29;12(1):13020. 2022-07-29 [PMID: 35906363] (Bioassay, Mouse)	Bioassay	Mouse
G Jacquemin, A Wurmser, M Huyghe, W Sun, Z Homayed, C Merle, M Perkins, F Qasrawi, S Richon, F Dingli, G Arras, D Loew, D Vignjevic, J Pannequin, S Fre Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme Elife, 2022-05-11;11(0):. 2022-05-11 [PMID: 35543624] (Bioassay, Mouse)	Bioassay	Mouse
Y Zhang, Y Wang, G Zheng, Y Liu, J Li, H Huang, C Xu, Y Zeng, X Zhang, J Qin, C Dai, HO Hambrock, U Hartmann, B Feng, KK Mak, Y Liu, HY Lan, Y Huang, ZH Zheng, Y Xia Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/beta-catenin signaling in obstructed kidneys in vivo The Journal of Biological Chemistry, 2022-05-04;0(0):102010. 2022-05-04 [PMID: 35525270] (Cell Culture, Mouse)	Cell Culture	Mouse
S Mancarella, G Serino, S Coletta, R Armentano, F Dituri, F Ardito, A Ruzzenente, I Fabregat, G Giannelli The Tumor Microenvironment Drives Intrahepatic Cholangiocarcinoma Progression International Journal of Molecular Sciences, 2022-04-10;23(8):. 2022-04-10 [PMID: 35457006] (Cell Culture, Mouse)	Cell Culture	Mouse
K Komatsu, H Ideno, T Shibata, K Nakashima, A Nifuji Platelet-derived growth factor-BB regenerates functional periodontal ligament in the tooth replantation Scientific Reports, 2022-02-25;12(1):3223. 2022-02-25 [PMID: 35217688] (Bioassay, Human)	Bioassay	Human
S Watanabe, S Kobayashi, N Ogasawara, R Okamoto, T Nakamura, M Watanabe, KB Jensen, S Yui Transplantation of intestinal organoids into a mouse model of colitis Nature Protocols, 2022-02-02;0(0):. 2022-02-02 [PMID: 35110738] (Bioassay, Mouse)	Bioassay	Mouse
CM Termini, A Pang, T Fang, M Roos, VY Chang, Y Zhang, NJ Setiawan, L Signaevska, M Li, MM Kim, O Tabibi, PK Lin, JP Sasine, A Chatterjee, R Murali, HA Himburg, JP Chute Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution Nature Communications, 2021-11-30;12(1):6990. 2021-11-30 [PMID: 34848712] (Bioassay, Mouse)	Bioassay	Mouse
RJ Geusz, A Wang, DK Lam, NK Vinckier, KD Alysandrat, DA Roberts, J Wang, S Kefalopoul, A Ramirez, Y Qiu, J Chiou, KJ Gaulton, B Ren, DN Kotton, M Sander Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors Nature Communications, 2021-11-17;12(1):6636. 2021-11-17 [PMID: 34789735] (Bioassay, Human)	Bioassay	Human
S Heino, S Fang, M Lähde, J Högström, S Nassiri, A Campbell, D Flanagan, A Raven, M Hodder, N Nasreddin, HH Xue, M Delorenzi, S Leedham, TV Petrova, O Sansom, K Alitalo Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas Science Advances, 2021-11-17;7(47):eabj0512. 2021-11-17 [PMID: 34788095] (Bioassay, Mouse)	Bioassay	Mouse
C Shen, A Nayak, LR Neitzel, AA Adams, M Silver-Ise, LM Sawyer, H Benchabane, H Wang, N Bunnag, B Li, DT Wynn, F Yang, M Garcia-Con, CH Williams, S Dakshanamu, CC Hong, NG Ayad, AJ Capobianco, Y Ahmed, E Lee, DJ Robbins The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling Nature Communications, 2021-09-06;12(1):5263. 2021-09-06 [PMID: 34489457] (Bioassay, Mouse)	Bioassay	Mouse
N Aaron, MJ Kraakman, Q Zhou, Q Liu, S Costa, J Yang, L Liu, L Yu, L Wang, Y He, L Fan, H Hirakawa, L Ding, J Lo, W Wang, B Zhao, E Guo, L Sun, CJ Rosen, L Qiang Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells Elife, 2021-06-22;10(0):. 2021-06-22 [PMID: 34155972] (Bioassay, Mouse)	Bioassay	Mouse
A Weinstock, K Rahman, O Yaacov, H Nishi, P Menon, CA Nikain, ML Garabedian, S Pena, N Akbar, BE Sansbury, SP Heffron, J Liu, G Marecki, D Fernandez, EJ Brown, KV Ruggles, SA Ramsey, C Giannarell, M Spite, RP Choudhury, P Loke, EA Fisher Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis Elife, 2021-03-15;10(0):. 2021-03-15 [PMID: 33720008] (Bioassay, Mouse)	Bioassay	Mouse
M Jurásek, J Kumar, P Paclíková, A Kumari, K Tripsianes, V Bryja, R Vácha Phosphorylation-induced changes in the PDZ domain of Dishevelled 3 Scientific Reports, 2021-01-15;11(1):1484. 2021-01-15 [PMID: 33452274] (Bioassay, Human)	Bioassay	Human
KA Radaszkiew, D Beckerová, L Woloszczuk, TW Radaszkiew, P Lesáková, OV Blaná?ová, L Kubala, P Humpolí?ek, J Pachernik 12-O-Tetradecanoylphorbol-13-acetate increases cardiomyogenesis through PKC/ERK signaling Sci Rep, 2020-09-28;10(1):15922. 2020-09-28 [PMID: 32985604] (Bioassay, Mouse)	Bioassay	Mouse
DP Bagchi, A Nishii, Z Li, JB DelPropost, CA Corsa, H Mori, J Hardij, BS Learman, CN Lumeng, OA MacDougald Wnt/&beta-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells Mol Metab, 2020-09-09;42(0):101078. 2020-09-09 [PMID: 32919095] (Cell Culture, Mouse)	Cell Culture	Mouse
Y Kiyokawa, M Sato, H Noguchi, E Inada, Y Iwase, N Kubota, T Sawami, M Terunuma, T Maeda, H Hayasaki, I Saitoh Drug-Induced Na�ve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic &beta-Cell Lineage Journal of Clinical Medicine, 2020-09-02;9(9):. 2020-09-02 [PMID: 32887316] (Bioassay, Human)	Bioassay	Human
Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, J Puschhof, C Pleguezuel, WC Peng, R Senlice, C Piani, JW Buikema, OM Gbenedio, M Vallon, J Yuan, S de Haan, W Hemrika, K Rösch, LT Dang, D Baker, M Ott, P Depeille, SM Wu, J Drost, R Nusse, JP Roose, J Piehler, SF Boj, CY Janda, H Clevers, CJ Kuo, KC Garcia Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In�Vivo Cell Stem Cell, 2020-08-19;0(0):. 2020-08-19 [PMID: 32818433] (Bioassay, Mouse)	Bioassay	Mouse
B Ma, TJ Trieu, J Cheng, S Zhou, Q Tang, J Xie, JL Liu, K Zhao, SJ Habib, X Chen Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells Cell Rep, 2020-08-11;32(6):108003. 2020-08-11 [PMID: 32783931] (Bioassay, Mouse)	Bioassay	Mouse
L Zhang, J Avery, A Yin, AM Singh, TS Cliff, H Yin, S Dalton Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State Cell Stem Cell, 2020-08-11;0(0):. 2020-08-11 [PMID: 32783886] (Bioassay, Human)	Bioassay	Human
SY Jeong, J Lyu, JA Kim, IH Oh Ryk modulates the niche activity of mesenchymal stromal cells by fine-tuning canonical Wnt signaling Exp. Mol. Med., 2020-07-28;0(0):. 2020-07-28 [PMID: 32724069] (Cell Culture, Mouse)	Cell Culture	Mouse
NK Vinckier, NA Patel, RJ Geusz, A Wang, J Wang, I Matta, AR Harrington, M Wortham, N Wetton, J Wang, US Jhala, MG Rosenfeld, CW Benner, HP Shih, M Sander LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development Nat Commun, 2020-04-29;11(1):2082. 2020-04-29 [PMID: 32350257] (Bioassay, Human)	Bioassay	Human
DP Bagchi, Z Li, CA Corsa, J Hardij, H Mori, BS Learman, KT Lewis, RL Schill, SM Romanelli, OA MacDougald Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction Mol Metab, 2020-04-20;0(0):100992. 2020-04-20 [PMID: 32325263] (Cell Culture, Mouse)	Cell Culture	Mouse
H Lee, YS Son, MO Lee, JW Ryu, K Park, O Kwon, KB Jung, K Kim, TY Ryu, A Baek, J Kim, CR Jung, CM Ryu, YJ Park, TS Han, DS Kim, HS Cho, MY Son Low-dose interleukin-2 alleviates dextran sodium sulfate-induced colitis in mice by recovering intestinal integrity and inhibiting AKT-dependent pathways Theranostics, 2020-04-06;10(11):5048-5063. 2020-04-06 [PMID: 32308767] (Cell Culture, Mouse)	Cell Culture	Mouse
D Gay, G Ghinatti, CF Guerrero-J, RA Ferrer, F Ferri, CH Lim, S Murakami, N Gault, V Barroca, I Rombeau, P Mauffrey, L Irbah, E Treffeisen, S Franz, A Boissonnas, C Combadière, M Ito, MV Plikus, PH Romeo Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing Sci Adv, 2020-03-20;6(12):eaay3704. 2020-03-20 [PMID: 32219160] (Cell Culture, Mouse)	Cell Culture	Mouse
I Betella, WJ Turbitt, T Szul, B Wu, A Martinez, A Katre, JA Wall, L Norian, MJ Birrer, R Arend Wnt signaling modulator DKK1 as an immunotherapeutic target in ovarian cancer Gynecol. Oncol., 2020-03-16;0(0):. 2020-03-16 [PMID: 32192732] (Cell Culture, Mouse)	Cell Culture	Mouse
M Mecha, N Yanguas-Ca, A Feliú, L Mestre, FJ Carrillo-S, K Riecken, D Gomez-Nico, C Guaza Involvement of Wnt7a in the role of M2c microglia in neural stem cell oligodendrogenesis J Neuroinflammation, 2020-03-19;17(1):88. 2020-03-19 [PMID: 32192522] (Cell Culture, Rat)	Cell Culture	Rat
A Kawashima, R Yasuhara, R Akino, K Mishima, M Nasu, A Sekizawa Engraftment potential of maternal adipose-derived stem cells for fetal transplantation Heliyon, 2020-03-04;6(3):e03409. 2020-03-04 [PMID: 32154403] (Cell Culture, Mouse)	Cell Culture	Mouse
Y Wada, A Kikuchi, A Kaga, N Shimizu, J Ito, R Onuma, F Fujishima, E Totsune, R Sato, T Niihori, M Shirota, R Funayama, K Sato, T Nakazawa, K Nakayama, Y Aoki, S Aiba, K Nakagawa, S Kure Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice PLoS Genet., 2020-02-26;16(2):e1008628. 2020-02-26 [PMID: 32101538] (Cell Culture, Mouse)	Cell Culture	Mouse
CJ Aros, MK Paul, CJ Pantoja, B Bisht, LK Meneses, P Vijayaraj, JM Sandlin, B France, JA Tse, MW Chen, DW Shia, TM Rickabaugh, R Damoiseaux, BN Gomperts High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis Cell Rep, 2020-02-18;30(7):2055-2064.e5. 2020-02-18 [PMID: 32075752] (Cell Culture, Mouse)	Cell Culture	Mouse
JP Sah, NTT Hao, X Han, TTT Tran, S McCarthy, Y Oh, JK Yoon Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/beta-Catenin signaling Int. J. Biochem. Cell Biol., 2019-12-02;118(0):105661. 2019-12-02 [PMID: 31805399] (Bioassay, Mouse)	Bioassay	Mouse
W Liang, P Han, EH Kim, J Mak, R Zhang, AG Torrente, JI Goldhaber, E Marbán, HC Cho Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells Stem Cells, 2019-12-30;0(0):. 2019-12-30 [PMID: 31648393] (Bioassay, Mouse)	Bioassay	Mouse
D Zhou, H Fu, Y Han, L Zhang, S Liu, L Lin, DB Stolz, Y Liu Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis JCI Insight, 2019-11-14;4(22):. 2019-11-14 [PMID: 31647783] (Bioassay, Rat)	Bioassay	Rat
N Chen, RL Schill, M O'Donnell, K Xu, DP Bagchi, OA MacDougald, RJ Koenig, B Xu The transcription factor NKX1-2 promotes adipogenesis and may contribute to a balance between adipocyte and osteoblast differentiation J. Biol. Chem., 2019-10-15;0(0):. 2019-10-15 [PMID: 31615896] (Bioassay, Mouse)	Bioassay	Mouse
C Lee, C Choi, HS Kang, SW Shin, SY Kim, HC Park, SN Hong NOD2 Supports Crypt Survival and Epithelial Regeneration after Radiation-Induced Injury Int J Mol Sci, 2019-09-02;20(17):. 2019-09-02 [PMID: 31480799] (Bioassay, Mouse)	Bioassay	Mouse
FM Cernilogar, S Hasenöder, Z Wang, K Scheibner, I Burtscher, M Sterr, P Smialowski, S Groh, IM Evenroed, GD Gilfillan, H Lickert, G Schotta Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2 Nucleic Acids Res., 2019-09-26;0(0):. 2019-09-26 [PMID: 31350899] (Cell Culture, Mouse)	Cell Culture	Mouse
S Saraswati, SMW Marrow, LA Watch, PP Young Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing Nat Commun, 2019-07-09;10(1):3027. 2019-07-09 [PMID: 31289275] (Cell Culture, Human)	Cell Culture	Human
C Yoon, J Till, SJ Cho, KK Chang, JX Lin, CM Huang, S Ryeom, SS Yoon KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis Mol. Cancer Res., 2019-06-19;0(0):. 2019-06-19 [PMID: 31217166] (Bioassay, Transgenic Mouse)	Bioassay	Transgenic Mouse
KL VanDussen, NM Sonnek, TS Stappenbec L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams Stem Cell Res, 2019-03-27;37(0):101430. 2019-03-27 [PMID: 30933720] (Bioassay, Human)	Bioassay	Human
P Shooshtari, A Helness, C Vadnais, N Brouwer, H Beauchemin, R Chen, H Bagci, FJT Staal, JF Coté, T Möröy Gfi1b regulates the level of Wnt/?-catenin signaling in hematopoietic stem cells and megakaryocytes Nat Commun, 2019-03-20;10(1):1270. 2019-03-20 [PMID: 30894540] (Bioassay, Mouse)	Bioassay	Mouse
M Chapellier, P Peña-Martí, R Ramakrishn, M Eriksson, M Safaee-Tal, C Orsmark-Pi, H Lilljebjör, C Högberg, A Hagström-A, T Fioretos, J Larsson, M Järås Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells Haematologica, 2019-02-28;0(0):. 2019-02-28 [PMID: 30819903] (Bioassay, Mouse)	Bioassay	Mouse
J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, YL Tay, A Ziaei, R Zeng, D Low, F Aminkeng, RM Sobota, F Ginhoux, E Petretto, MA Pouladi Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects Cell Rep, 2019-02-26;26(9):2494-2508.e7. 2019-02-26 [PMID: 30811996] (Bioassay, Human)	Bioassay	Human
L Qian, H Zhang, Y Gu, D Li, S He, H Wang, Y Cheng, W Yang, H Yu, X Zhao, W Cai, L Meng, M Jin, Y Wang, Y Zhang Reduced production of laminin by hepatic stellate cells contributes to impairment in oval cell response to liver injury in aged mice Aging (Albany NY), 2018-12-04;0(0):. 2018-12-04 [PMID: 30513510] (Bioassay, Mouse)	Bioassay	Mouse
YB Hu, C Yan, L Mu, YL Mi, H Zhao, H Hu, XL Li, DD Tao, YQ Wu, JP Gong, JC Qin Exosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance Oncogene, 2018-11-02;0(0):. 2018-11-02 [PMID: 30390075] (Bioassay, Human)	Bioassay	Human
S Olabi, A Ucar, K Brennan, CH Streuli Integrin-Rac signalling for mammary epithelial stem cell self-renewal Breast Cancer Res., 2018-10-22;20(1):128. 2018-10-22 [PMID: 30348189] (Bioassay, Mouse)	Bioassay	Mouse
A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids Elife, 2018-10-12;7(0):. 2018-10-12 [PMID: 30311909] (Bioassay, Human)	Bioassay	Human
Y Xie, ES Park, D Xiang, Z Li Long-term organoid culture reveals enrichment of organoid-forming epithelial cells in the fimbrial portion of mouse fallopian tube Stem Cell Res, 2018-08-25;32(0):51-60. 2018-08-25 [PMID: 30176443] (Bioassay, Mouse)	Bioassay	Mouse
A Spangler, EY Su, AM Craft, P Cahan A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo Stem Cell Res, 2018-07-29;31(0):201-215. 2018-07-29 [PMID: 30118958] (Bioassay, Mouse)	Bioassay	Mouse
P Andersen, E Tampakakis, DV Jimenez, S Kannan, M Miyamoto, HK Shin, A Saberi, S Murphy, E Sulistio, SP Chelko, C Kwon Precardiac organoids form two heart fields via Bmp/Wnt signaling Nat Commun, 2018-08-07;9(1):3140. 2018-08-07 [PMID: 30087351] (Mouse)		Mouse
E López-Arri, V Rodilla, C Colomer, A Vert, A Shelton, JH Cheng, B Yan, A Gonzalez-P, MR Junttila, M Iglesias, F Torres, J Albanell, A Villanueva, A Bigas, CW Siebel, L Espinosa Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells Nat Commun, 2018-07-31;9(1):2992. 2018-07-31 [PMID: 30065304] (Bioassay, Mouse)	Bioassay	Mouse
HE Ahrens, J Huettemeis, M Schmidt, C Kaether, J von Maltza Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle Skelet Muscle, 2018-07-04;8(1):20. 2018-07-04 [PMID: 29973273] (Bioassay, Mouse)	Bioassay	Mouse
Y Muta, Y Fujita, K Sumiyama, A Sakurai, MM Taketo, T Chiba, H Seno, K Aoki, M Matsuda, M Imajo Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine Nat Commun, 2018-06-05;9(1):2174. 2018-06-05 [PMID: 29872037] (Mouse)		Mouse
JA Ríos, JA Godoy, NC Inestrosa Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis Cell Commun. Signal, 2018-04-11;16(1):15. 2018-04-11 [PMID: 29642895] (Bioassay, Rat)	Bioassay	Rat
K Matsuoka, Y Kohara, Y Naoe, A Watanabe, M Ito, K Ikeda, S Takeshita WAIF1 is a cell-surface CTHRC1 binding protein coupling bone resorption and formation J. Bone Miner. Res., 2018-05-11;0(0):. 2018-05-11 [PMID: 29624737] (Bioassay, Mouse)	Bioassay	Mouse
W Liu, X Xu, Z Fan, G Sun, Y Han, D Zhang, L Xu, M Wang, X Wang, S Zhang, M Tang, J Li, R Chai, H Wang Wnt signaling activates TIGAR and protects against cisplatin-induced spiral ganglion neuron damage in the mouse cochlea Antioxid. Redox Signal., 2018-05-04;0(0):. 2018-05-04 [PMID: 29587485] (Bioassay, Mouse)	Bioassay	Mouse
A Held, A Glas, L Dietrich, M Bollmann, K Brandstädt, TN Grossmann, CH Lohmann, T Pap, J Bertrand Targeting ?-catenin dependent Wnt signaling via peptidomimetic inhibitors in murine chondrocytes and OA cartilage Osteoarthr. Cartil., 2018-03-17;0(0):. 2018-03-17 [PMID: 29559252] (Bioassay, Mouse)	Bioassay	Mouse
Y Kasagi, PM Chandramou, KA Whelan, K Tanaka, V Giroux, M Sharma, J Wang, AJ Benitez, M DeMarshall, JW Tobias, KE Hamilton, GW Falk, JM Spergel, AJ Klein-Szan, AK Rustgi, AB Muir, H Nakagawa The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial�Changes Cell Mol Gastroenterol Hepatol, 2018-01-03;5(3):333-352. 2018-01-03 [PMID: 29552622] (Organoid Culture, Mouse)	Organoid Culture	Mouse
YY Sin, LL Ballantyne, CR Richmond, CD Funk Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice Mol Ther Nucleic Acids, 2017-12-01;10(0):122-130. 2017-12-01 [PMID: 29499927] (Bioassay, Mouse)	Bioassay	Mouse
J Li, X Wu, Y Zhou, M Lee, L Guo, W Han, W Mo, WM Cao, D Sun, R Xie, Y Huang Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC Nucleic Acids Res., 2018-04-06;0(0):. 2018-04-06 [PMID: 29394393] (Bioassay, Human)	Bioassay	Human
F Zhao, C Xiao, KS Evans, T Theivanthi, N DeVito, A Holtzhause, J Liu, X Liu, D Boczkowski, S Nair, JW Locasale, BA Hanks Paracrine Wnt5a-?-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization Immunity, 2018-01-16;48(1):147-160.e7. 2018-01-16 [PMID: 29343435] (Cell Culture, Mouse)	Cell Culture	Mouse
MH Kwack, JM Yang, GH Won, MK Kim, JC Kim, YK Sung Establishment and characterization of five immortalized human scalp dermal papilla cell lines Biochem. Biophys. Res. Commun., 2018-01-10;0(0):. 2018-01-10 [PMID: 29331373] (Bioassay, Human)	Bioassay	Human
Y Chen, H Xu, G Lin Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse Cell Discov, 2017-12-19;3(0):17046. 2017-12-19 [PMID: 29263795] (Bioassay, Mouse)	Bioassay	Mouse
MW Susman, EP Karuna, RC Kunz, TS Gujral, AV Cantú, SS Choi, BY Jong, K Okada, MK Scales, J Hum, LS Hu, MW Kirschner, R Nishinakam, S Yamada, DJ Laird, LE Jao, SP Gygi, ME Greenberg, HH Ho Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates Elife, 2017-09-08;6(0):. 2017-09-08 [PMID: 28885975] (Bioassay, Mouse)	Bioassay	Mouse
KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, S Mejia-Guer, Y Aghazadeh, JL Rourke, RA Screaton, M Grompe, PR Streeter, AC Powers, M Brissova, T Kislinger, MC Nostro Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors Nat Commun, 2017-08-24;8(1):331. 2017-08-24 [PMID: 28835709] (Bioassay, Human)	Bioassay	Human
B Li, C Dorrell, PS Canaday, C Pelz, A Haft, M Finegold, M Grompe Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes Stem Cell Reports, 2017-07-06;0(0):. 2017-07-06 [PMID: 28689996] (Bioassay, Mouse)	Bioassay	Mouse
M Lowndes, S Junyent, SJ Habib Constructing cellular niche properties by localized presentation of Wnt proteins on synthetic surfaces Nat Protoc, 2017-06-29;12(7):1498-1512. 2017-06-29 [PMID: 28686585] (Bioassay, Mouse)	Bioassay	Mouse
P Paclíková, O Bernatík, TW Radaszkiew, V Bryja N-terminal part of Dishevelled DEP domain is required for Wnt/?-catenin signaling in mammalian cells Mol. Cell. Biol., 2017-08-28;0(0):. 2017-08-28 [PMID: 28674183] (Bioassay, Human)	Bioassay	Human
YY Sin, PR Price, LL Ballantyne, CD Funk Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency Sci Rep, 2017-05-31;7(1):2585. 2017-05-31 [PMID: 28566761] (Bioassay, Mouse)	Bioassay	Mouse
T Tammela, FJ Sanchez-Ri, NM Cetinbas, K Wu, NS Joshi, K Helenius, Y Park, R Azimi, NR Kerper, RA Wesselhoef, X Gu, L Schmidt, M Cornwall-B, ÖH Yilmaz, W Xue, P Katajisto, A Bhutkar, T Jacks A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma Nature, 2017-05-10;545(7654):355-359. 2017-05-10 [PMID: 28489818] (Bioassay, Mouse)	Bioassay	Mouse
ZZ Wei, JY Zhang, TM Taylor, X Gu, Y Zhao, L Wei Neuroprotective and regenerative roles of intranasal Wnt-3a Administration after focal ischemic stroke in mice J. Cereb. Blood Flow Metab., 2017-04-21;0(0):271678X177026. 2017-04-21 [PMID: 28430000] (In Vivo, Mouse)	In Vivo	Mouse
Y Zhang Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/?-catenin signaling Biochem. Biophys. Res. Commun., 2017-04-17;0(0):. 2017-04-17 [PMID: 28427938] (Bioassay, Mouse)	Bioassay	Mouse
KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling Cell Stem Cell, 2017-03-30;0(0):. 2017-03-30 [PMID: 28366587] (Bioassay, Mouse)	Bioassay	Mouse
K Wilk, SA Yeh, LJ Mortensen, S Ghaffariga, CM Lombardo, SH Bassir, ZA Aldawood, CP Lin, G Intini Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration Stem Cell Reports, 2017-03-30;0(0):. 2017-03-30 [PMID: 28366454] (Bioassay, Mouse)	Bioassay	Mouse
MB Furtado, JC Wilmanns, A Chandran, J Perera, O Hon, C Biben, TJ Willow, HT Nim, G Kaur, S Simonds, Q Wu, D Willians, E Salimova, N Plachta, JM Denegre, SA Murray, D Fatkin, M Cowley, JT Pearson, D Kaye, M Ramialison, RP Harvey, NA Rosenthal, MW Costa Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling JCI Insight, 2017-03-23;2(6):e88271. 2017-03-23 [PMID: 28352650] (Bioassay, Human)	Bioassay	Human
J Zhang, J Zhang, C Qi, P Yang, X Chen, Y Liu Activation of Wnt3?/?-catenin signal pathway attenuates apoptosis of the cerebral microvascular endothelial cells induced by oxygen-glucose deprivation Biochem. Biophys. Res. Commun, 2017-03-25;0(0):. 2017-03-25 [PMID: 28347817] (Bioassay, Mouse)	Bioassay	Mouse
L Li, X Peng, Y Qin, R Wang, J Tang, X Cui, T Wang, W Liu, H Pan, B Li Acceleration of bone regeneration by activating Wnt/?-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis Sci Rep, 2017-03-24;7(0):45204. 2017-03-24 [PMID: 28338064] (Bioassay, Mouse)	Bioassay	Mouse
F Lacour, E Vezin, CF Bentzinger, MC Sincennes, L Giordani, A Ferry, R Mitchell, K Patel, MA Rudnicki, MC Chaboissie, AA Chassot, F Le Grand R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways Cell Rep, 2017-03-07;18(10):2320-2330. 2017-03-07 [PMID: 28273449] (Bioassay, Mouse)	Bioassay	Mouse
MJ Rodríguez-, M Schewe, M Meerlo, E Stigter, J Gerrits, M Pras-Raves, A Sacchetti, M Hornsveld, KC Oost, HJ Snippert, N Verhoeven-, R Fodde, BM Burgering Interplay between metabolic identities in the intestinal crypt supports stem cell function Nature, 2017-03-08;543(7645):424-427. 2017-03-08 [PMID: 28273069] (Bioassay, Mouse)	Bioassay	Mouse
N Cerdá-Este, H Naumann, S Ruzittu, N Mah, IM Pongrac, C Cozzitorto, A Hommel, MA Andrade-Na, E Bonifacio, FM Spagnoli Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2 Nat Commun, 2017-02-13;8(0):14127. 2017-02-13 [PMID: 28193997] (Bioassay, Mouse)	Bioassay	Mouse
Lebensohn A, Dubey R, Neitzel L, Tacchelly-Benites O, Yang E, Marceau C, Davis E, Patel B, Bahrami-Nejad Z, Travaglini K, Ahmed Y, Lee E, Carette J, Rohatgi R Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. Elife, 2016-12-20;5(0):. 2016-12-20 [PMID: 27996937] (Bioassay, Human)	Bioassay	Human
Hoeke A Baarsma Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD J. Exp. Med, 2016-12-15;0(0):. 2016-12-15 [PMID: 27979969] (Bioassay, Mouse)	Bioassay	Mouse
Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms Nat. Med, 2016-12-05;0(0):. 2016-12-05 [PMID: 27918563] (Bioassay, Mouse)	Bioassay	Mouse
Joan Massagué The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells Cell Stem Cell, 2016-11-23;0(0):. 2016-11-23 [PMID: 27889317] (Bioassay, Mouse)	Bioassay	Mouse
Muruganandan S, Govindarajan R, McMullen N, Sinal C Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation. Stem Cells, 2016-11-11;35(3):711-724. 2016-11-11 [PMID: 27733019] (Bioassay, Mouse)	Bioassay	Mouse
Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose PLoS ONE, 2016-09-23;11(9):e0163580. 2016-09-23 [PMID: 27662374] (Bioassay, Mouse)	Bioassay	Mouse
Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism PLoS ONE, 2016-08-26;11(8):e0162049. 2016-08-26 [PMID: 27564706] (Bioassay, Mouse)	Bioassay	Mouse
Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a-induced Autophagy in Pancreatic Intraepithelial Neoplasms J Biol Chem, 2016-08-24;0(0):. 2016-08-24 [PMID: 27557659] (Bioassay, Mouse)	Bioassay	Mouse
Diverse Functions of Retinoic Acid in Brain Vascular Development J Neurosci, 2016-07-20;36(29):7786-801. 2016-07-20 [PMID: 27445154] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Ting Cai WNT/?-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression Exp Cell Res, 2016-06-16;0(0):. 2016-06-16 [PMID: 27321958] (Bioassay, Rat)	Bioassay	Rat
CM Karner, E Esen, J Chen, FF Hsu, J Turk, F Long Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation J. Biol. Chem., 2016-04-20;291(25):13028-39. 2016-04-20 [PMID: 27129247] (Bioassay, Mouse)	Bioassay	Mouse
PJ Attayek, AA Ahmad, Y Wang, I Williamson, CE Sims, ST Magness, NL Allbritton In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment PLoS ONE, 2016-04-21;11(4):e0153795. 2016-04-21 [PMID: 27100890] (Bioassay, Mouse)	Bioassay	Mouse
Marie-Isabelle Garcia Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage Development, 2016-03-17;143(9):1452-63. 2016-03-17 [PMID: 26989172] (Bioassay, Mouse)	Bioassay	Mouse
Morrison G, Scognamiglio R, Trumpp A, Smith A Convergence of cMyc and beta-catenin on Tcf7l1 enables endoderm specification. EMBO J, 2015-12-16;35(3):356-68. 2015-12-16 [PMID: 26675138] (Bioassay, Mouse)	Bioassay	Mouse
Lu W, Bird T, Boulter L, Tsuchiya A, Cole A, Hay T, Guest R, Wojtacha D, Man T, Mackinnon A, Ridgway R, Kendall T, Williams M, Jamieson T, Raven A, Hay D, Iredale J, Clarke A, Sansom O, Forbes S Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nat Cell Biol, 2015-07-20;17(8):971-83. 2015-07-20 [PMID: 26192438] (Bioassay, Mouse)	Bioassay	Mouse
Beier E, Sheu T, Dang D, Holz J, Ubayawardena R, Babij P, Puzas J Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/beta-CATENIN SIGNALING PATHWAY. J Biol Chem, 2015-05-14;290(29):18216-26. 2015-05-14 [PMID: 25975268] (Bioassay, Mouse)	Bioassay	Mouse
Chang B, Tessneer K, McManus J, Liu X, Hahn S, Pasula S, Wu H, Song H, Chen Y, Cai X, Dong Y, Brophy M, Rahman R, Ma J, Xia L, Chen H Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. Nat Commun, 2015-03-16;6(0):6380. 2015-03-16 [PMID: 25871009] (Bioassay, Mouse)	Bioassay	Mouse
Amador-Arjona , Alejandr, Cimadamore , Flavio, Huang , Chun-Ten, Wright , Rebecca, Lewis , Susan, Gage , Fred H, Terskikh , Alexey V SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proc Natl Acad Sci U S A, 2015-03-30;112(15):E1936-45. 2015-03-30 [PMID: 25825708] (Bioassay, Mouse)	Bioassay	Mouse
Suzuki A, Pelikan R, Iwata J WNT/beta-Catenin Signaling Regulates Multiple Steps of Myogenesis by Regulating Step-Specific Targets. Mol Cell Biol, 2015-03-09;35(10):1763-76. 2015-03-09 [PMID: 25755281] (Bioassay, Mouse)	Bioassay	Mouse
Suryawanshi A, Manoharan I, Hong Y, Swafford D, Majumdar T, Taketo M, Manicassamy B, Koni P, Thangaraju M, Sun Z, Mellor A, Munn D, Manicassamy S Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation. J Immunol, 2015-02-20;194(7):3295-304. 2015-02-20 [PMID: 25710911] (Bioassay, Mouse)	Bioassay	Mouse
Zhang L, Chen P, Chen L, Weng T, Zhang S, Zhou X, Zhang B, Liu L Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) mice. PLoS ONE, 2015-02-18;10(2):e112716. 2015-02-18 [PMID: 25693202] (Bioassay, Mouse)	Bioassay	Mouse
Tao S, Tang D, Morita Y, Sperka T, Omrani O, Lechel A, Sakk V, Kraus J, Kestler H, Kuhl M, Rudolph K Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage. EMBO J, 2015-01-21;34(5):624-40. 2015-01-21 [PMID: 25609789] (Bioassay, Mouse)	Bioassay	Mouse
Alshbool F, Mohan S Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis. PLoS ONE, 2014-12-05;9(12):e114357. 2014-12-05 [PMID: 25479235] (Bioassay, Mouse)	Bioassay	Mouse
Ramsey S, Vengrenyuk Y, Menon P, Podolsky I, Feig J, Aderem A, Fisher E, Gold E Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway. PLoS Genet, 2014-12-04;10(12):e1004828. 2014-12-04 [PMID: 25474352] (Bioassay, Mouse)	Bioassay	Mouse
Ouji Y, Ishizaka S, Nakamura-Uchiyama F, Okuzaki D, Yoshikawa M Partial maintenance and long-term expansion of murine skin epithelial stem cells by Wnt-3a in vitro. J Invest Dermatol, 2014-12-01;135(6):1598-608. 2014-12-01 [PMID: 25437427] (Bioassay, Mouse)	Bioassay	Mouse
Noguchi , H, Saitoh , I, Tsugata , T, Kataoka , H, Watanabe , M, Noguchi , Y Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection. Cell Death Differ, 2014-09-05;22(1):145-55. 2014-09-05 [PMID: 25190146] (Bioassay, Mouse)	Bioassay	Mouse
Gouti , Mina, Tsakiridis , Anestis, Wymeersch , Filip J, Huang , Yali, Kleinjung , Jens, Wilson , Valerie, Briscoe , James In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol, 2014-08-26;12(8):e1001937. 2014-08-26 [PMID: 25157815] (Bioassay, Mouse)	Bioassay	Mouse
Komiya Y, Mandrekar N, Sato A, Dawid I, Habas R Custos controls beta-catenin to regulate head development during vertebrate embryogenesis. Proc Natl Acad Sci U S A, 2014-08-25;111(36):13099-104. 2014-08-25 [PMID: 25157132] (Bioassay, Human)	Bioassay	Human
Cambier L, Plate M, Sucov H, Pashmforoush M Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. Development, 2014-08-01;141(15):2959-71. 2014-08-01 [PMID: 25053429] (Bioassay, Mouse)	Bioassay	Mouse
Zhu Q, Song L, Peng G, Sun N, Chen J, Zhang T, Sheng N, Tang W, Qian C, Qiao Y, Tang K, Han J, Li J, Jing N The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways. Elife, 2014-06-14;3(0):. 2014-06-14 [PMID: 24929964] (Bioassay, Mouse)	Bioassay	Mouse
Gao B, Huang Q, Lin Y, Wei B, Guo Y, Sun Z, Wang L, Fan J, Zhang H, Han Y, Li X, Shi J, Liu J, Yang L, Luo Z Dose-dependent effect of estrogen suppresses the osteo-adipogenic transdifferentiation of osteoblasts via canonical Wnt signaling pathway. PLoS ONE, 2014-06-11;9(6):e99137. 2014-06-11 [PMID: 24918446] (Bioassay, Mouse)	Bioassay	Mouse
Zhu , Yunhua, Demidov , Oleg N, Goh , Amanda M, Virshup , David M, Lane , David P, Bulavin , Dmitry V Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J Clin Invest, 2014-06-09;124(7):3263-73. 2014-06-09 [PMID: 24911145] (Bioassay, Mouse)	Bioassay	Mouse
Poh Y, Chen J, Hong Y, Yi H, Zhang S, Chen J, Wu D, Wang L, Jia Q, Singh R, Yao W, Tan Y, Tajik A, Tanaka T, Wang N Generation of organized germ layers from a single mouse embryonic stem cell. Nat Commun, 2014-05-30;5(0):4000. 2014-05-30 [PMID: 24873804] (Bioassay, Mouse)	Bioassay	Mouse
Weinert S, Jabs S, Hohensee S, Chan W, Kornak U, Jentsch T Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions. EMBO Rep, 2014-05-12;15(7):784-91. 2014-05-12 [PMID: 24820037] (Bioassay, Mouse)	Bioassay	Mouse
Bentzinger C, von Maltzahn J, Dumont N, Stark D, Wang Y, Nhan K, Frenette J, Cornelison D, Rudnicki M Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J Cell Biol, 2014-04-07;205(1):97-111. 2014-04-07 [PMID: 24711502] (Bioassay, Mouse)	Bioassay	Mouse
Koraishy F, Silva C, Mason S, Wu D, Cantley L Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling. J Biol Chem, 2014-04-01;289(20):14341-50. 2014-04-01 [PMID: 24692544] (Bioassay, Mouse)	Bioassay	Mouse
Okamoto M, Udagawa N, Uehara S, Maeda K, Yamashita T, Nakamichi Y, Kato H, Saito N, Minami Y, Takahashi N, Kobayashi Y Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis. Sci Rep, 2014-03-27;4(0):4493. 2014-03-27 [PMID: 24670389] (Bioassay, Mouse)	Bioassay	Mouse
Yu C, Nguyen T, Irvine K, Sweet M, Frazer I, Blumenthal A Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. Eur J Immunol, 2014-03-07;44(5):1480-90. 2014-03-07 [PMID: 24643512] (Bioassay, Mouse)	Bioassay	Mouse
Lewandowski J, Pursell T, Rabinowitz A, Vokes S Manipulating gene expression and signaling activity in cultured mouse limb bud cells. Dev Dyn, 2014-04-17;243(7):928-36. 2014-04-17 [PMID: 24633820] (Bioassay, Mouse)	Bioassay	Mouse
Tsakiridis , Anestis, Huang , Yali, Blin , Guillaum, Skylaki , Stavroul, Wymeersch , Filip, Osorno , Rodrigo, Economou , Costas, Karagianni , Eleni, Zhao , Suling, Lowell , Sally, Wilson , Valerie Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Development, 2014-03-01;141(6):1209-21. 2014-03-01 [PMID: 24595287] (Bioassay, Mouse)	Bioassay	Mouse
Liu Y, Kaneda R, Leja T, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz R, Barahona M, Schneider M Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells. Stem Cells, 2014-06-01;32(6):1515-26. 2014-06-01 [PMID: 24585688] (Bioassay, Mouse)	Bioassay	Mouse
Go G, Srivastava R, Hernandez-Ono A, Gang G, Smith S, Booth C, Ginsberg H, Mani A The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. Cell Metab, 2014-02-04;19(2):209-20. 2014-02-04 [PMID: 24506864] (Bioassay, Mouse)	Bioassay	Mouse
Chen J, Tu X, Esen E, Joeng K, Lin C, Arbeit J, Ruegg M, Hall M, Ma L, Long F WNT7B promotes bone formation in part through mTORC1. PLoS Genet, 2014-01-30;10(1):e1004145. 2014-01-30 [PMID: 24497849] (Bioassay, Mouse)	Bioassay	Mouse
Raggioli A, Junghans D, Rudloff S, Kemler R Beta-catenin is vital for the integrity of mouse embryonic stem cells. PLoS ONE, 2014-01-21;9(1):e86691. 2014-01-21 [PMID: 24466203] (Bioassay, Mouse)	Bioassay	Mouse
Stapp A, Gomez B, Gifford C, Hallford D, Hernandez Gifford J Canonical WNT signaling inhibits follicle stimulating hormone mediated steroidogenesis in primary cultures of rat granulosa cells. PLoS ONE, 2014-01-17;9(1):e86432. 2014-01-17 [PMID: 24466091] (Bioassay, Rat)	Bioassay	Rat
Lei N, Jabaji Z, Wang J, Joshi V, Brinkley G, Khalil H, Wang F, Jaroszewicz A, Pellegrini M, Li L, Lewis M, Stelzner M, Dunn J, Martin M Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells. PLoS ONE, 2014-01-06;9(1):e84651. 2014-01-06 [PMID: 24400106] (Bioassay, Mouse)	Bioassay	Mouse
Dhamdhere , Girija R, Fang , Mark Y, Jiang , Jie, Lee , Katherin, Cheng , Du, Olveda , Rebecca, Liu , Bo, Mulligan , Kimberle, Carlson , Jeffery, Ransom , Ryan C, Weis , William, Helms , Jill A Drugging a stem cell compartment using Wnt3a protein as a therapeutic. PLoS ONE, 2014-01-06;9(1):e83650. 2014-01-06 [PMID: 24400074] (Bioassay, Mouse)	Bioassay	Mouse
Kohler , Erin E, Wary , Kishore, Li , Fei, Chatterjee , Ishita, Urao , Norifumi, Toth , Peter T, Ushio-Fukai , Masuko, Rehman , Jalees, Park , Changwon, Malik , Asrar B Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells. PLoS ONE, 2013-12-30;8(12):e85549. 2013-12-30 [PMID: 24386480] (In Vivo, Mouse)	In Vivo	Mouse
Ishikawa M, Iwamoto T, Fukumoto S, Yamada Y Pannexin 3 inhibits proliferation of osteoprogenitor cells by regulating Wnt and p21 signaling. J Biol Chem, 2013-12-12;289(5):2839-51. 2013-12-12 [PMID: 24338011] (Bioassay, Mouse)	Bioassay	Mouse
Boschert V, van Dinther M, Weidauer S, van Pee K, Muth E, ten Dijke P, Mueller T Mutational analysis of sclerostin shows importance of the flexible loop and the cystine-knot for Wnt-signaling inhibition. PLoS ONE, 2013-11-29;8(11):e81710. 2013-11-29 [PMID: 24312339] (Bioassay, Human)	Bioassay	Human
Stalvey M, Clines K, Havasi V, McKibbin C, Dunn L, Chung W, Clines G Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease. PLoS ONE, 2013-11-13;8(11):e80098. 2013-11-13 [PMID: 24236172] (Bioassay, Mouse)	Bioassay	Mouse
Nishino , Jinsuke, Kim , Sunjung, Zhu , Yuan, Zhu , Hao, Morrison , Sean J A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife, 2013-11-05;2(0):e00924. 2013-11-05 [PMID: 24192035] (Bioassay, Mouse)	Bioassay	Mouse
Salazar V, Zarkadis N, Huang L, Watkins M, Kading J, Bonar S, Norris J, Mbalaviele G, Civitelli R Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with beta-catenin. J Cell Sci, 2013-10-07;126(0):5598-609. 2013-10-07 [PMID: 24101723] (Bioassay, Mouse)	Bioassay	Mouse
Xavier C, Melikova M, Chuman Y, Uren A, Baljinnyam B, Rubin J Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/beta-catenin signaling. Cell Signal, 2013-09-28;26(1):94-101. 2013-09-28 [PMID: 24080158] (Bioassay, Mouse)	Bioassay	Mouse
Yang J, Wang J, Pan L, Li H, Rao C, Zhang X, Niu G, Qu J, Hou L BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells. Exp Cell Res, 2013-09-27;320(1):54-61. 2013-09-27 [PMID: 24080013] (Bioassay, Mouse)	Bioassay	Mouse
Zhou , Wei-Jie, Geng , Zhen H, Spence , Jason R, Geng , Jian-Guo Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection. Nature, 2013-07-31;501(7465):107-11. 2013-07-31 [PMID: 23903657] (Cell Culture, Mouse)	Cell Culture	Mouse
Busch A, Johnson K, Stan R, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle S Evidence for tankyrases as antineoplastic targets in lung cancer. BMC Cancer, 2013-04-28;13(0):211. 2013-04-28 [PMID: 23621985] (Bioassay, Mouse)	Bioassay	Mouse
Huynh D, Akcora D, Malaterre J, Chan C, Dai X, Bertoncello I, Stanley E, Ramsay R CSF-1 receptor-dependent colon development, homeostasis and inflammatory stress response. PLoS ONE, 2013-02-22;8(2):e56951. 2013-02-22 [PMID: 23451116] (Bioassay, Mouse)	Bioassay	Mouse
Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury. Proc Natl Acad Sci U S A, 2013-01-23;110(6):2324-9. 2013-01-23 [PMID: 23345421] (Bioassay, Mouse)	Bioassay	Mouse
Mae , Shin-Ich, Shono , Akemi, Shiota , Fumihiko, Yasuno , Tetsuhik, Kajiwara , Masatosh, Gotoda-Nishimura , Nanaka, Arai , Sayaka, Sato-Otubo , Aiko, Toyoda , Taro, Takahashi , Kazutosh, Nakayama , Naoki, Cowan , Chad A, Aoi , Takashi, Ogawa , Seishi, McMahon , Andrew P, Yamanaka , Shinya, Osafune , Kenji Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun, 2013-01-01;4(0):1367. 2013-01-01 [PMID: 23340407] (Bioassay, Human)	Bioassay	Human
Nakamura , Tetsuya, Saito , Daisuke, Kawasumi , Aiko, Shinohara , Kyosuke, Asai , Yasuko, Takaoka , Katsuyos, Dong , Fenglan, Takamatsu , Atsuko, Belo , Jose Ant, Mochizuki , Atsushi, Hamada , Hiroshi Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA. Nat Commun, 2012-01-01;3(0):1322. 2012-01-01 [PMID: 23271656] (Bioassay, Mouse)	Bioassay	Mouse
Halleskog C, Schulte G Pertussis toxin-sensitive heterotrimeric G(alphai/o) proteins mediate WNT/beta-catenin and WNT/ERK1/2 signaling in mouse primary microglia stimulated with purified WNT-3A. Cell Signal, 2012-12-22;25(4):822-8. 2012-12-22 [PMID: 23266471] (Bioassay, Mouse)	Bioassay	Mouse
Sneddon , Julie B, Borowiak , Malgorza, Melton , Douglas Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature, 2012-10-07;491(7426):765-8. 2012-10-07 [PMID: 23041930] (Mouse)		Mouse
Walker , Tara L, Vukovic , Jana, Koudijs , Margaret, Blackmore , Daniel G, Mackay , Eirinn W, Sykes , Alex M, Overall , Rupert W, Hamlin , Adam S, Bartlett , Perry F Prolactin stimulates precursor cells in the adult mouse hippocampus. PLoS ONE, 2012-09-04;7(9):e44371. 2012-09-04 [PMID: 22973440] (Bioassay, Mouse)	Bioassay	Mouse
Tran , Thanh H, Shi , Xiaofeng, Zaia , Joseph, Ai , Xingbin Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration. J Biol Chem, 2012-08-03;287(39):32651-64. 2012-08-03 [PMID: 22865881] (Bioassay, Mouse)	Bioassay	Mouse
Tran H, Polakis P Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the beta-catenin destruction complex. J Biol Chem, 2012-07-03;287(34):28552-63. 2012-07-03 [PMID: 22761442] (Bioassay, Human)	Bioassay	Human
Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis. Cell Death Differ., 2012-05-04;19(11):1761-8. 2012-05-04 [PMID: 22555459] (Bioassay, Human)	Bioassay	Human
Goel S, Chin EN, Fakhraldeen SA Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts. J. Biol. Chem., 2012-03-20;287(20):16454-66. 2012-03-20 [PMID: 22433869] (Bioassay, Mouse)	Bioassay	Mouse
Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). J. Biol. Chem., 2012-02-15;287(15):12016-26. 2012-02-15 [PMID: 22337886] (Bioassay, Mouse)	Bioassay	Mouse
Wang P, McKnight K, Wong D, Rodriguez R, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang H, Kim S A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells Dev, 2012-02-29;21(12):2273-87. 2012-02-29 [PMID: 22236333] (Bioassay, Mouse)	Bioassay	Mouse
Kelly OG, Chan MY, Martinson LA Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells. Nat. Biotechnol., 2011-07-31;29(8):750-6. 2011-07-31 [PMID: 21804561] (Bioassay, Human)	Bioassay	Human
Tsai SY, Bouwman BA, Ang YS, Kim SJ, Lee DF, Lemischka IR, Rendl M Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells, 2011-06-01;29(6):964-71. 2011-06-01 [PMID: 21563278] (Bioassay, Mouse)	Bioassay	Mouse
Krause C, Korchynskyi O, de Rooij K, Weidauer SE, de Gorter DJ, van Bezooijen RL, Hatsell S, Economides AN, Mueller TD, Lowik CW, ten Dijke P Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways. J. Biol. Chem., 2010-10-15;285(53):41614-26. 2010-10-15 [PMID: 20952383] (Bioassay, Mouse)	Bioassay	Mouse
Del Debbio CB, Balasubramanian S, Parameswaran S, Chaudhuri A, Qiu F, Ahmad I Notch and Wnt signaling mediated rod photoreceptor regeneration by Muller cells in adult mammalian retina. PLoS ONE, 2010-08-26;5(8):e12425. 2010-08-26 [PMID: 20865053] (Bioassay, Mouse)	Bioassay	Mouse
Gong Y, Bourhis E, Chiu C, Stawicki S, DeAlmeida VI, Liu BY, Phamluong K, Cao TC, Carano RA, Ernst JA, Solloway M, Rubinfeld B, Hannoush RN, Wu Y, Polakis P, Costa M Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies. PLoS ONE, 2010-09-13;5(9):e12682. 2010-09-13 [PMID: 20856934] (Binding Assay, Human)	Binding Assay	Human
Roelandt P, Pauwelyn KA, Sancho-Bru P Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS ONE, 2010-08-11;5(8):e12101. 2010-08-11 [PMID: 20711405] (Cell Culture, Rat)	Cell Culture	Rat
Trowbridge JJ, Guezguez B, Moon RT Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity. Stem Cells, 2010-08-01;28(8):1379-89. 2010-08-01 [PMID: 20521329] (Bioassay, Mouse)	Bioassay	Mouse
Gustafson B, Smith U Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance. J. Biol. Chem., 2010-02-23;285(18):14031-41. 2010-02-23 [PMID: 20179324] (Bioassay, Mouse)	Bioassay	Mouse
Kawaguchi J, Nichols J, Gierl MS, Faial T, Smith A Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development, 2010-03-01;137(5):693-704. 2010-03-01 [PMID: 20147374] (Bioassay, Mouse)	Bioassay	Mouse
Steele BM, Harper MT, Macaulay IC, Morrell CN, Perez-Tamayo A, Foy M, Habas R, Poole AW, Fitzgerald DJ, Maguire PB Canonical Wnt signaling negatively regulates platelet function. Proc. Natl. Acad. Sci. U.S.A., 2009-11-09;106(47):19836-41. 2009-11-09 [PMID: 19901330] (Bioassay, Human)	Bioassay	Human
Gogolla N, Galimberti I, Deguchi Y, Caroni P Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron, 2009-05-28;62(4):510-25. 2009-05-28 [PMID: 19477153] (In Vivo, Mouse)	In Vivo	Mouse
Hansson M, Olesen DR, Peterslund JM, Engberg N, Kahn M, Winzi M, Klein T, Maddox-Hyttel P, Serup P A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. Dev. Biol., 2009-04-07;330(2):286-304. 2009-04-07 [PMID: 19358838] (Bioassay, Mouse)	Bioassay	Mouse
Shafer SL, Towler DA Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol., 2009-01-21;46(5):621-35. 2009-01-21 [PMID: 19344627] (Bioassay, Mouse)	Bioassay	Mouse
Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell, 2009-04-03;4(4):348-58. 2009-04-03 [PMID: 19341624] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Liu CC, Pearson C, Bu G Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains. J. Biol. Chem., 2009-03-31;284(22):15299-307. 2009-03-31 [PMID: 19339249] (Bioassay, Receptor Binding Assay, Human)	Bioassay, Receptor Binding Assay	Human
Kim SE, Yoon JY, Jeong WJ, Jeon SH, Park Y, Yoon JB, Park YN, Kim H, Choi KY H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation. J. Cell. Sci., 2009-02-24;122(0):842-8. 2009-02-24 [PMID: 19240121] (In Vivo, Mouse)	In Vivo	Mouse
Wan M, Yang C, Li J, Wu X, Yuan H, Ma H, He X, Nie S, Chang C, Cao X Parathyroid hormone signaling through low-density lipoprotein-related protein 6. Genes Dev., 2008-11-01;22(21):2968-79. 2008-11-01 [PMID: 18981475] (In Vivo, Mouse)	In Vivo	Mouse
Verkaar F, van Rosmalen JW, Smits JF, Blankesteijn WM, Zaman GJ Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells. Cell. Signal., 2008-09-25;21(1):22-33. 2008-09-25 [PMID: 18929644] (Bioassay, Human)	Bioassay	Human
Kennell JA, Gerin I, MacDougald OA, Cadigan KM The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc. Natl. Acad. Sci. U.S.A., 2008-09-29;105(40):15417-22. 2008-09-29 [PMID: 18824696] (Bioassay, Mouse)	Bioassay	Mouse
Nakanishi M, Kurisaki A, Hayashi Y, Warashina M, Ishiura S, Kusuda-Furue M, Asashima M Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium. FASEB J., 2008-09-22;23(1):114-22. 2008-09-22 [PMID: 18809738] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Endo Y, Beauchamp E, Woods D, Taylor WG, Toretsky JA, Uren A, Rubin JS Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol. Cell. Biol., 2008-01-22;28(7):2368-79. 2008-01-22 [PMID: 18212053] (Bioassay, Human)	Bioassay	Human
Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev., 2008-01-15;22(2):152-65. 2008-01-15 [PMID: 18198334] (Bioassay, Human)	Bioassay	Human
Anderson BC, Christiansen SP, McLoon LK Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest. Ophthalmol. Vis. Sci., 2008-01-01;49(1):221-9. 2008-01-01 [PMID: 18172096] (In Vivo, Rabbit)	In Vivo	Rabbit
Cho YM, Lim JM, Yoo DH, Kim JH, Chung SS, Park SG, Kim TH, Oh SK, Choi YM, Moon SY, Park KS, Lee HK Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells. Biochem. Biophys. Res. Commun., 2007-12-04;366(1):129-34. 2007-12-04 [PMID: 18060872] (Bioassay, Human)	Bioassay	Human
Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood, 2007-11-27;111(4):1933-41. 2007-11-27 [PMID: 18042803] (Bioassay, Human)	Bioassay	Human
Giuliani N, Morandi F, Tagliaferri S, Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer Res., 2007-08-15;67(16):7665-74. 2007-08-15 [PMID: 17702698] (Bioassay, Human)	Bioassay	Human
Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc. Natl. Acad. Sci. U.S.A., 2007-06-18;104(26):10894-9. 2007-06-18 [PMID: 17576928] (Bioassay, Mouse)	Bioassay	Mouse
Rydziel S, Stadmeyer L, Zanotti S, Durant D, Smerdel-Ramoya A, Canalis E Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. J. Biol. Chem., 2007-05-10;282(27):19762-72. 2007-05-10 [PMID: 17500060] (Bioassay, Mouse)	Bioassay	Mouse
Wawrzak D, Metioui M, Willems E, Hendrickx M, de Genst E, Leyns L Wnt3a binds to several sFRPs in the nanomolar range. Biochem. Biophys. Res. Commun., 2007-04-19;357(4):1119-23. 2007-04-19 [PMID: 17462603] (Bioassay, Mouse)	Bioassay	Mouse
Canning CA, Lee L, Irving C, Mason I, Jones CM Sustained interactive Wnt and FGF signaling is required to maintain isthmic identity. Dev. Biol., 2007-02-16;305(1):276-86. 2007-02-16 [PMID: 17383629] (Bioassay, Chicken)	Bioassay	Chicken
Miyabayashi T, Teo JL, Yamamoto M, McMillan M, Nguyen C, Kahn M Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc. Natl. Acad. Sci. U.S.A., 2007-03-19;104(13):5668-73. 2007-03-19 [PMID: 17372190] (Bioassay, Mouse)	Bioassay	Mouse
Nordstrom U, Maier E, Jessell TM, Edlund T An early role for WNT signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. PLoS Biol., 2006-07-01;4(8):e252. 2006-07-01 [PMID: 16895440] (Bioassay, Chicken)	Bioassay	Chicken
Yue Z, Jiang TX, Widelitz RB, Chuong CM Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc. Natl. Acad. Sci. U.S.A., 2006-01-17;103(0):951-5. 2006-01-17 [PMID: 16418297] (In Vivo, Chicken)	In Vivo	Chicken
Corti S, Locatelli F, Papadimitriou D, Donadoni C, Del Bo R, Fortunato F, Strazzer S, Salani S, Bresolin N, Comi GP Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells. FASEB J., 2005-09-08;19(13):1860-2. 2005-09-08 [PMID: 16150803] (Bioassay, Mouse)	Bioassay	Mouse
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Array 1324-WN/CF

• Wnt-3a Antibodies
• Wnt-3a ELISA Kit
• Wnt-3a Lysate
• Wnt-3a Proteins
• Wnt-3a Proteins and Enzymes
• Wnt-3a ELISA