Novus Biologicals products are now on bio-techne.com

Rab5a Antibody (C4)

Images

 
Immunohistochemistry-Paraffin: Rab5a Antibody (C4) [NBP3-41678] - DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 30ug/ml NBP3-41678; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal ...read more
Immunohistochemistry-Paraffin: Rab5a Antibody (C4) [NBP3-41678] - DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 30ug/ml NBP3-41678; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal ...read more

Product Details

Summary
Reactivity Hu, Rt, PoSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
C4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Rab5a Antibody (C4) Summary

Immunogen
Immunized with recombinant Human Rab5a (Uniprot#: P20339; Met1-Ser214 (Uniprot#: P20339)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RAB5A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Rab5a Antibody (C4)

  • RAB5A, member RAS oncogene family
  • RAB5RAS-associated protein RAB5A
  • ras-related protein Rab-5A

Background

Rab5 is a 24 kDa GTP-binding protein that regulates the fusion of plasma membrane -derived clathrin-coated vesicles with early endosomes , and homotypic fusion among early endosomes1. Localized to the cytoplasmic side of the plasma membrane, clathrin -coated vesicles and early endosomes, Rab5 appears to regulate vesicle fusion through a cycle of GDP/GTP e xchange and GTP hydrolysis. The different guanine nuc leotide binding states of Rab5 may affect its ability to associate or dissociate with membranes during endocytotic membrane traffic. The GTP-bound, or active, form of Rab5 associates with membrane s and regulates vesicle docking and fusion. Studies using a Rab5 mutant that hydrolyzed xanthosine 5 -triphosphate (XTP) indicated that nucleotide hydrolysis occurs even in the absence of membrane fusion. GTP hydrolysis by Rab5 may determine the frequency of membrane docking and fusion events.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-87174
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, KD, WB
H00338382-M01
Species: Hu
Applications: ELISA, IP, WB
NBP1-91991
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-36568
Species: Hu, Mu
Applications: Flow-IC, ICC/IF, IHC, IHC-P, WB
NBP2-49320
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-37485
Species: Hu, Pm, Mu, Pm
Applications: CyTOF-ready, ELISA, Flow, IHC, IHC-P, WB
2914-HT
Species: Hu
Applications: BA
AF231
Species: Hu
Applications: CyTOF-ready, Dual ISH-IHC, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, ICC, IHC, IP, Simple Western, WB
236-EG
Species: Hu
Applications: BA
NBP1-82590
Species: Hu
Applications: IHC, IHC-P, WB
NBP1-49938
Species: Hu, Mu
Applications: IHC, IHC-P, IP, WB
NB110-68800
Species: Hu, Mu
Applications: ICC/IF, WB
NB120-19294
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP3-13291
Species: Mu, Rt
Applications: WB
AF6260
Species: Hu
Applications: WB
NBP1-33110
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, KO, WB
AF887
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
NBP2-21577
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD, WB

Publications for Rab5a Antibody (NBP3-41678) (0)

There are no publications for Rab5a Antibody (NBP3-41678).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Rab5a Antibody (NBP3-41678) (0)

There are no reviews for Rab5a Antibody (NBP3-41678). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Rab5a Antibody (NBP3-41678) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Rab5a Products

Research Areas for Rab5a Antibody (NBP3-41678)

Find related products by research area.

Blogs on Rab5a

There are no specific blogs for Rab5a, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Rab5a Antibody (C4) and receive a gift card or discount.

Bioinformatics

Gene Symbol RAB5A