Protein Disulfide Isomerase/P4HB Antibody

P4HB, the beta subunit of prolyl 4-hydroxylase, a highly abundant member of the PDI family. P4HB is a multifunctional enzyme, involved in hydroxylation of prolyl residues in preprocollagen, as well as continual rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 6 confirmed species: Human, Mouse, Rat, Porcine, Primate, Sheep.

We have publications tested in 3 applications: ICC/IF, IP, WB.

Showing Publications 1 - 10 of 10.

Publications using NBP1-97470	Applications	Species
S Lindquist et al. Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev. 22, 3308 . 2008-01-01 [PMID: 19015277] (WB, Human)	WB	Human
K Brix et al. Trafficking of lysosomal cathepsin B-green fluorescent protein to the surface of thyroid epithelial cells involves the endosomal/lysosomal compartment. J. Cell. Sci. 115, 4877 . 2002-01-01 [PMID: 12432075] (ICC/IF, Rat)	ICC/IF	Rat
DE Vance et al. Membrane topography of human phosphatidylethanolamine N-methyltransferase. J. Biol. Chem. 278, 2956 . 2003-01-01 [PMID: 12431977] (WB, Mouse)	WB	Mouse
Venkataraman K, Riebeling C, Bodennec J et al. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J Biol Chem 2002-09-20 [PMID: 12105227] (ICC/IF, Primate)	ICC/IF	Primate
J Dean et al. Conserved furin cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice. Mol. Cell. Biol. 22, 3111 . 2002-01-01 [PMID: 11940668] (ICC/IF, Mouse)	ICC/IF	Mouse
G Warren et al. Partitioning of the matrix fraction of the Golgi apparatus during mitosis in animal cells. Science 295, 848 . 2002-01-01 [PMID: 11823640] (WB, Rat)	WB	Rat
MH Doolittle et al. Maturation of lipoprotein lipase in the endoplasmic reticulum: concurrent formation of functional dimers and inactive aggregates. J. Biol. Chem. 277, 10727 . 2002-01-01 [PMID: 11796709] (IP, Human)	IP	Human
I Merida et al. Type I alpha phosphatidylinositol 4-phosphate 5-kinase is a putative target for increased intracellular phosphatidic acid. FEBS Lett. 476, 160 . 2000-01-01 [PMID: 10913605] (ICC/IF, Porcine)	ICC/IF	Porcine
P Klappa et al. Specificity in substrate binding by protein folding catalysts: tyrosine and tryptophan residues are the recognition motifs for the binding of peptides to the pancreas-specific protein disulfide isomerase PDIp. Protein Sci. 9, 758 . 2000-01-01 [PMID: 10794419] (WB, Sheep)	WB	Sheep
R Miquelis et al. Protein-disulfide isomerase (PDI) in FRTL5 cells - pH-dependent thyroglobulin/PDI interactions determine a novel PDI function in the post-endoplasmic reticulum of thyrocytes. J. Biol. Chem. 275, 1920 . 2000-01-01 [PMID: 10636893] (IP, Rat)	IP	Rat

Array NBP1-97470

• Protein Disulfide Isomerase/P4HB Antibodies
• Protein Disulfide Isomerase/P4HB Antibody Pair
• Protein Disulfide Isomerase/P4HB ELISA Kits
• Protein Disulfide Isomerase/P4HB Lysate
• Protein Disulfide Isomerase/P4HB Proteins
• Protein Disulfide Isomerase/P4HB Proteins and Enzyme