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Proteasome 20S alpha 3 Antibody [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

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Proteasome 20S alpha 3 Antibody [DyLight 650] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human Proteasome 20S alpha 3 (Accession#: AAH29402.1; Met1-Met255)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PSMA3
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Proteasome 20S alpha 3 Antibody [DyLight 650]

  • EC 3.4.25.1
  • HC8
  • HC8MGC32631
  • Macropain subunit C8
  • MGC12306
  • Multicatalytic endopeptidase complex subunit C8
  • proteasome (prosome, macropain) subunit, alpha type, 3
  • Proteasome 20S alpha 3
  • Proteasome component C8
  • proteasome subunit alpha type-3
  • proteasome subunit C8
  • PSC3
  • PSC8
  • PSMA3

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PSMA3