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Presenilin-1 Antibody - BSA Free

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Western Blot: Presenilin 1 Antibody [NB200-130] - Analysis of Human Presenilin 1 / PSDR1 in androgen-stimulated metastatic adenocarcinoma LNCaP.FGC cells with Presenilin 1 antibody at a dilution of 1:500

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Presenilin-1 Antibody - BSA Free Summary

Immunogen
Synthetic peptides corresponding to the N terminal sequence MVELMFP and the C terminal sequence LLGLPID of the human Presenilin 1 protein.
Specificity
Reacts with N terminal sequence MVELMFP and the C terminal sequence LLGLPID of the human Presenilin 1 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PSEN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot
Application Notes
This Presenilin 1 antibody is useful for Immunoprecipitation, Immunohistochemistry frozen and paraffin embedded sections and ELISA.
Control
Presenilin-1 Overexpression Lysate

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Presenilin-1 Antibody - BSA Free

  • AD3EC 3.4.23.-
  • Alzheimer disease 3
  • EC 3.4.23
  • FAD
  • presenilin 1
  • Presenilin1
  • Presenilin-1
  • Protein S182
  • PS-1
  • PS1presenilin-1
  • PSEN1
  • PSNL1
  • S182

Background

Presenilin 1 is a novel prostate short-chain dehydrogenase/reductase that exhibits increased expression on exposure to androgens in the LNCaP prostate cancer cell line. Presenilin 1 is expressed in normal and neoplastic prostate epithelium and is implicated in the pathogenesis of prostate carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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FAQs for Presenilin-1 Antibody (NB200-130) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Blogs on Presenilin-1.

Mechanisms of Neurodegeneration: Protein aggregation and failure of autophagy
By Michalina Hanzel, PhDIn a series of three blog posts I will briefly explore the major cellular mechanisms responsible for many neurodegenerative disorders. The first, and perhaps the most apparent, is the accumulat...  Read full blog post.

Immunity’s flipside: Microglia promote Alzheimer’s pathology during inflammation
By Jamshed Arslan Pharm.D. Microglia are brain's macrophages. In Alzheimer's disease (AD), microglia clear up protein aggregates called amyloid beta plaques. The connection between immune activation and AD is unclea...  Read full blog post.

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Bioinformatics

Gene Symbol PSEN1
Entrez