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PPP1R9B/Spinophilin Antibody - Azide and BSA Free

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Western Blot: PPP1R9B/Spinophilin Antibody [NBP2-94055] - Analysis of extracts of various cell lines, using PPP1R9B/Spinophilin at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. ...read more
Immunocytochemistry/ Immunofluorescence: PPP1R9B/Spinophilin Antibody [NBP2-94055] - Analysis of L929 cells using PPP1R9B/Spinophilin at dilution of 1:100. Blue: DAPI for nuclear staining.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

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PPP1R9B/Spinophilin Antibody - Azide and BSA Free Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PPP1R9B/Spinophilin (NP_115984.3). VFQPPPPPPPAPSGDAPAEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAASPAPEEPKAQA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP1R9B
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Western Blot 1:500-1:2000
Theoretical MW
89 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for PPP1R9B/Spinophilin Antibody - Azide and BSA Free

  • FLJ30345
  • neurabin II
  • Neurabin-2
  • neurabin-II
  • PPP1R6
  • PPP1R9
  • PPP1R9B
  • Protein phosphatase 1 regulatory subunit 9B
  • protein phosphatase 1, regulatory (inhibitor) subunit 9B
  • protein phosphatase 1, regulatory subunit 9B, spinophilin
  • SPINO
  • Spinophilin
  • Spn

Background

Spinophilin, also known as Neurabin-2 and PPP1R9B, has 815 amino acids and is approximately 89kDa. Spinophilin is a scaffold protein that is involved in many signaling pathways, such as the cAMP pathway, the G-protein coupled receptor signaling pathway, the IL-6 pathway, and the Beta-Adrenergic signaling pathway. Spinophilin may be implicated in the linking of the plasma membrane to the actin cytoskeleton at synaptic junctions. Current research on Spinophilin is being performed in relation to several diseases and disorders including anorexia nervosa, Alzheimer's disease, schizophrenia, encephalitis, breast cancer, mood disorder, and glioblastoma. Spinophilin has also been shown to have interactions with CCKAR, CCKBR, ADRA1B, DRD2, and PPP1CA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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Bioinformatics

Gene Symbol PPP1R9B