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PP2C beta/PPM1B Antibody

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Western Blot: PP2C beta/PPM1B Antibody [NBP3-30782] - Legend: Novus Biologicals' rabbit anti PP 2 A/B alpha/beta western blotting of total rat brain extract. Blocked with specific peptide (+). Note: Novus Biologicals' rabbit anti PP 2 A/B alpha/beta also readily detects recombinant PP 2 C alpha and PP 2 C beta.
Western Blot: PP2C beta/PPM1B Antibody [NBP3-30782] - Legend: Novus Biologicals' rabbit anti PP 2 A/B alpha/beta western blotting of total rat brain extract. Blocked with specific peptide (+). Note: Novus Biologicals' ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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PP2C beta/PPM1B Antibody Summary

Immunogen
The purified peptide conjugated to KLH.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPM1B
Purity
Ammonium sulfate precipitation
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Applications/Dilutions

Dilutions
  • Immunoprecipitation : 5-10ug/ml
  • Western Blot : 5-10ug/ml
Application Notes
.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.08% Sodium Azide
Purity
Ammonium sulfate precipitation

Alternate Names for PP2C beta/PPM1B Antibody

  • EC 3.1.3.16
  • MGC21657
  • PP2C beta
  • Pp2c2
  • PP2CB
  • PP2C-beta
  • PP2C-beta-X
  • PP2CBmagnesium-dependent, beta isoform
  • PPM1B
  • protein phosphatase 1B
  • Protein phosphatase 2C isoform beta
  • protein phosphatase 2C-like protein
  • protein phosphatase, Mg2+/Mn2+ dependent, 1B

Background

PPM1B is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PPM1B