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Polypeptide GalNac Transferase 3/GALNT3 Antibody

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Immunocytochemistry/ Immunofluorescence: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Polypeptide GalNac Transferase 3/GALNT3 antibody detects Polypeptide GalNac Transferase 3/GALNT3 protein at Golgi ...read more
Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Polypeptide GalNac Transferase 3/GALNT3 antibody detects Polypeptide GalNac Transferase 3/GALNT3 protein at Golgi apparatus ...read more
Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Polypeptide GalNac Transferase 3/GALNT3 antibody detects Polypeptide GalNac Transferase 3/GALNT3 protein at Golgi apparatus ...read more
Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Polypeptide GalNac Transferase 3/GALNT3 antibody detects Polypeptide GalNac Transferase 3/GALNT3 protein at Golgi apparatus ...read more
Immunocytochemistry/ Immunofluorescence: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Polypeptide GalNac Transferase 3/GALNT3 antibody detects Polypeptide GalNac Transferase 3/GALNT3 protein at Golgi ...read more
Western Blot: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Polypeptide GalNac Transferase ...read more
Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP3-13034] - Polypeptide GalNac Transferase 3/GALNT3 antibody detects Polypeptide GalNac Transferase 3/GALNT3 protein at Golgi apparatus ...read more

Product Details

Summary
Reactivity Hu, Mu, BvSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Polypeptide GalNac Transferase 3/GALNT3 Antibody Summary

Description
Centrifuge briefly prior to opening.
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human Polypeptide GalNac Transferase 3/GALNT3. The exact sequence is proprietary.
Predicted Species
Bovine (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GALNT3
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Reactivity Notes

Mouse (86%), Rat (87%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.025% Proclin 300
Purity
Antigen Affinity-purified

Alternate Names for Polypeptide GalNac Transferase 3/GALNT3 Antibody

  • EC 2.4.1.41
  • GalNAc transferase 3
  • GalNAc-T3
  • GalNAc-T3DKFZp686C10199
  • GALNT3
  • HFTC
  • HFTCMGC61909
  • HHS
  • HHSPolypeptide GalNAc transferase 3
  • polypeptide GalNAc-transferase T3
  • polypeptide N-acetylgalactosaminyltransferase 3
  • pp-GaNTase 3
  • Protein-UDP acetylgalactosaminyltransferase 3
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 3 (GalNAc-T3)

Background

GALNT3, also known as Polypeptide N-acetylgalactosaminyltransferase 3, has a 633 amino acid long isoform that is 73 kDa and a short 192 amino acid isoform that is 22 kDa; is located in the Golgi apparatus; plays a central role in phosphate homeostasis; acts as a catalyzer in the initiation of O-linked oligosaccharide biosynthesis, and the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor; shows an activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5; and glycosylates FGF23, and probably fibronectin in vivo too. Studies on this protein have shown a relationship with the following diseases and disorders: tumoral calcinosis, hyperphosphatemic calcinosis, hyperostosis-hyperphosphatemia syndrome, hyperphosphatemic familial tunoral calcinisis, normophosphatemic familial tumoral calcinosis, testicular microlithiasis, bile duct carcinoma, periostitis, squamous cell carcinoma, diabetes mellitus, colon adenocarcinoma, lung adenocarcinoma, pancreatic cancer, metabolic disorders, and lung cancer. This protein has also been shown to have interactions with CIGALT1, CIGALT1C1, ST6GALNAC1, B3GNT6, and GCNT1 in pathways such as O-linked glycosylation of mucins, metabolism of proteins, and post-translational protein modification.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol GALNT3